3MV8

Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG

Summary for 3MV8

• Entry DOI: 10.2210/pdb3mv8/pdb
• Related: 2fyy 3MV7 3MV9
• Descriptor: HLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, HPVG peptide from Epstein-Barr nuclear antigen 1, ... (7 entities in total)
• Functional Keywords: hla b*3501, ebv, tcr, tcrpmhc complex, hpvg, tcr polymorphism, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30685; Secreted: P61769; Host nucleus: P03211
• Total number of polymer chains: 5
• Total formula weight: 94750.84

Authors

Gras, S.,Chen, Z.,Miles, J.J.,Liu, Y.C.,Bell, M.J.,Sullivan, L.C.,Kjer-Nielsen, L.,Brennan, R.M.,Burrows, J.M.,Neller, M.A.,Khanna, R.,Purcell, A.W.,Brooks, A.G.,McCluskey, J.,Rossjohn, J.,Burrows, S.R. (deposition date: 2010-05-03, release date: 2010-06-09, Last modification date: 2011-07-20)

• Primary citation: Gras, S.,Chen, Z.,Miles, J.J.,Liu, Y.C.,Bell, M.J.,Sullivan, L.C.,Kjer-Nielsen, L.,Brennan, R.M.,Burrows, J.M.,Neller, M.A.,Khanna, R.,Purcell, A.W.,Brooks, A.G.,McCluskey, J.,Rossjohn, J.,Burrows, S.R.; Allelic polymorphism in the T cell receptor and its impact on immune responses; J.Exp.Med., 207:1555-1567, 2010; PubMed: 20566715; DOI: 10.1084/jem.20100603

Experimental method

X-RAY DIFFRACTION (2.1 Å)