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8IC0
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BU of 8ic0 by Molmil
Cryo-EM structure of CXCL8 bound C-X-C chemokine receptor 1 in complex with Gi heterotrimer
分子名称: C-X-C chemokine receptor type 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Ishimoto, N, Park, J.H, Park, S.Y.
登録日2023-02-10
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structural basis of CXC chemokine receptor 1 ligand binding and activation.
Nat Commun, 14, 2023
7XBD
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BU of 7xbd by Molmil
Cryo-EM structure of human galanin receptor 2
分子名称: Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Ishimoto, N, Kita, S, Park, S.Y.
登録日2022-03-21
公開日2022-07-13
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.
Plos Biol., 20, 2022
7FCI
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BU of 7fci by Molmil
human NTCP in complex with YN69083 Fab
分子名称: Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter
著者Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y.
登録日2021-07-14
公開日2022-05-25
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
8H2G
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BU of 8h2g by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2022-10-06
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism
To Be Published
7WJ5
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BU of 7wj5 by Molmil
Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
分子名称: Gai1 antibody (scfv16), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Heo, Y.S, Yoon, E.J, Jeon, Y.E, Yun, J.-H, Ishimoto, N, Woo, H, Park, S.Y, Song, J, Lee, W.T.
登録日2022-01-05
公開日2022-07-13
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity.
Elife, 11, 2022
8I7W
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BU of 8i7w by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-02-02
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8I7V
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BU of 8i7v by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-02-02
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5C
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BU of 8k5c by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8HRX
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BU of 8hrx by Molmil
Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
8HRY
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BU of 8hry by Molmil
Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9016, Fab light chain from antibody IgG clone number YN9016, Large S protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
7VDN
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BU of 7vdn by Molmil
High resolution crystal structure of Sperm Whale Myoglobin in the carbonmonoxy form
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Shibayama, N, Sato-Tomita, A, Ishimoto, N, Park, S.Y.
登録日2021-09-07
公開日2022-09-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献X-ray fluorescence holography of biological metal sites: Application to myoglobin.
Biochem.Biophys.Res.Commun., 635, 2022
6JYA
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BU of 6jya by Molmil
Structure of dark-state marine bacterial chloride importer, NM-R3, with CW laser (ND-10%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JYF
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BU of 6jyf by Molmil
Structure of light-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 140K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JYE
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BU of 6jye by Molmil
Structure of dark-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 140K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JY6
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BU of 6jy6 by Molmil
Structure of dark-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JYC
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BU of 6jyc by Molmil
Structure of dark-state marine bacterial chloride importer, NM-R3, with CW laser (ND-30%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JY8
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BU of 6jy8 by Molmil
Structure of dark-state marine bacterial chloride importer, NM-R3, with CW laser (ND-3%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JY7
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BU of 6jy7 by Molmil
Structure of light-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JYD
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BU of 6jyd by Molmil
Structure of light-state marine bacterial chloride importer, NM-R3, with CW laser (ND-30%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JY9
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BU of 6jy9 by Molmil
Structure of light-state marine bacterial chloride importer, NM-R3, with CW laser (ND-3%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
6JYB
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BU of 6jyb by Molmil
Structure of light-state marine bacterial chloride importer, NM-R3, with CW laser (ND-10%) at 95K.
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Ohki, M, Park, S.Y, Lee, W.
登録日2019-04-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020

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