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8BOT
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BU of 8bot by Molmil
Cryo-EM structure of NHEJ supercomplex(trimer)
分子名称: DNA (24-MER), DNA (27-MER), DNA (28-MER), ...
著者Hardwick, S.W, Chaplin, A.K.
登録日2022-11-15
公開日2023-06-28
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (7.76 Å)
主引用文献Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.
Structure, 31, 2023
2J6Y
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BU of 2j6y by Molmil
Structural and Functional Characterisation of partner switching regulating the environmental stress response in Bacillus subtilis
分子名称: PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
2J6Z
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BU of 2j6z by Molmil
Structural and functional characterisation of partner-switching regulating the environmental stress response in B. subtilis
分子名称: PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
2J70
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BU of 2j70 by Molmil
Structural and functional characterisation of partner-switching regulating the environmental stress response in B. subtilis
分子名称: PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
4AM3
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BU of 4am3 by Molmil
Crystal structure of C. crescentus PNPase bound to RNA
分子名称: PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RNA, ...
著者Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F.
登録日2012-03-07
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Open Biol., 2, 2012
4AIM
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BU of 4aim by Molmil
Crystal structure of C. crescentus PNPase bound to RNase E recognition peptide
分子名称: PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RIBONUCLEASE, ...
著者Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F.
登録日2012-02-10
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Open Biol., 2, 2012
4AID
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BU of 4aid by Molmil
Crystal structure of C. crescentus PNPase bound to RNase E recognition peptide
分子名称: PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RIBONUCLEASE, ...
著者Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F.
登録日2012-02-09
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Open Biol., 2, 2012
7ZVT
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BU of 7zvt by Molmil
CryoEM structure of Ku heterodimer bound to DNA
分子名称: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*T)-3'), DNA (5'-D(P*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*TP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ...
著者Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K.
登録日2022-05-17
公開日2023-05-24
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Nucleic Acids Res., 51, 2023
7ZWA
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BU of 7zwa by Molmil
CryoEM structure of Ku heterodimer bound to DNA and PAXX
分子名称: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ...
著者Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K.
登録日2022-05-19
公開日2023-05-31
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
7ZYG
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BU of 7zyg by Molmil
CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF
分子名称: DNA, Non-homologous end-joining factor 1, PHOSPHATE ION, ...
著者Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K.
登録日2022-05-24
公開日2023-06-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BHY
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BU of 8bhy by Molmil
DNA-PK Ku80 mediated dimer bound to PAXX and XLF
分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
著者Hardwick, S.W, Chaplin, A.K.
登録日2022-11-01
公開日2023-06-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (5.33 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BH3
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BU of 8bh3 by Molmil
DNA-PK Ku80 mediated dimer bound to PAXX
分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
著者Hardwick, S.W, Chaplin, A.K.
登録日2022-10-28
公開日2023-06-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BHV
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BU of 8bhv by Molmil
DNA-PK XLF mediated dimer bound to PAXX
分子名称: DNA (24-MER), DNA (26-MER), DNA (27-MER), ...
著者Hardwick, S.W, Chaplin, A.K.
登録日2022-11-01
公開日2023-06-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.51 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
6GWK
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BU of 6gwk by Molmil
The crystal structure of Hfq from Caulobacter crescentus
分子名称: RNA-binding protein Hfq
著者Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W.
登録日2018-06-25
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
7A4M
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BU of 7a4m by Molmil
Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A
分子名称: FE (III) ION, Ferritin heavy chain, ZINC ION
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-20
公開日2020-10-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (1.22 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
7A5V
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BU of 7a5v by Molmil
CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-22
公開日2020-11-18
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (1.7 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
6ZHE
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BU of 6zhe by Molmil
Cryo-EM structure of DNA-PK dimer
分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-23
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.24 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZH4
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BU of 6zh4 by Molmil
Cryo-EM structure of DNA-PKcs (State 3)
分子名称: DNA-dependent protein kinase catalytic subunit,DNA-PKcs
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-20
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZH6
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BU of 6zh6 by Molmil
Cryo-EM structure of DNA-PKcs:Ku80ct194
分子名称: DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-21
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZFP
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BU of 6zfp by Molmil
Cryo-EM structure of DNA-PKcs (State 2)
分子名称: DNA-dependent protein kinase catalytic subunit,DNA-PKcs,DNA-PKcs
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-17
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZHA
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BU of 6zha by Molmil
Cryo-EM structure of DNA-PK monomer
分子名称: DNA, DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5, ...
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-21
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZH8
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BU of 6zh8 by Molmil
Cryo-EM structure of DNA-PKcs:DNA
分子名称: DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*T)-3'), DNA-dependent protein kinase catalytic subunit,DNA-PKcs
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-21
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZH2
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BU of 6zh2 by Molmil
Cryo-EM structure of DNA-PKcs (State 1)
分子名称: DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-20
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
2YJV
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BU of 2yjv by Molmil
Crystal structure of E. coli regulator of ribonuclease activity A (RraA) bound to fragment of DEAD-box protein RhlB
分子名称: ATP-DEPENDENT RNA HELICASE RHLB, REGULATOR OF RIBONUCLEASE ACTIVITY A
著者Pietras, Z, Hardwick, S.W, Luisi, B.F.
登録日2011-05-24
公開日2012-06-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Potential regulatory interactions of Escherichia coli RraA protein with DEAD-box helicases.
J. Biol. Chem., 288, 2013
2YJT
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BU of 2yjt by Molmil
Crystal structure of E. coli DEAD-box protein SrmB bound to regulator of ribonuclease activity A (RraA)
分子名称: ATP-DEPENDENT RNA HELICASE SRMB, REGULATOR OF RIBONUCLEASE ACTIVITY A
著者Pietras, Z, Hardwick, S.W, Luisi, B.F.
登録日2011-05-23
公開日2012-06-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Potential Regulatory Interactions of Escherichia Coli Rraa Protein with Dead-Box Helicases.
J.Biol.Chem., 288, 2013

 

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