6ZH2
Cryo-EM structure of DNA-PKcs (State 1)
Summary for 6ZH2
| Entry DOI | 10.2210/pdb6zh2/pdb |
| EMDB information | 11211 |
| Descriptor | DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs (1 entity in total) |
| Functional Keywords | kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 472056.28 |
| Authors | Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2020-06-20, release date: 2020-10-21, Last modification date: 2021-01-20) |
| Primary citation | Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L. Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28:13-19, 2021 Cited by PubMed: 33077952DOI: 10.1038/s41594-020-00517-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.92 Å) |
Structure validation
Download full validation report
