Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2A5S
DownloadVisualize
BU of 2a5s by Molmil
Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate
分子名称: GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit
著者Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
登録日2005-06-30
公開日2005-11-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
2A5T
DownloadVisualize
BU of 2a5t by Molmil
Crystal Structure Of The NR1/NR2A ligand-binding cores complex
分子名称: GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ...
著者Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
登録日2005-06-30
公開日2005-11-15
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
1PB7
DownloadVisualize
BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
分子名称: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB8
DownloadVisualize
BU of 1pb8 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
分子名称: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
DownloadVisualize
BU of 1pb9 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
分子名称: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PBQ
DownloadVisualize
BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
分子名称: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-07-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
6CNA
DownloadVisualize
BU of 6cna by Molmil
GluN1-GluN2B NMDA receptors with exon 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Furukawa, H, Grant, T, Grigorieff, N.
登録日2018-03-07
公開日2018-10-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
3OEM
DownloadVisualize
BU of 3oem by Molmil
Crystal structure of GluN2D ligand-binding core in complex with N-methyl-D-aspartate
分子名称: Glutamate [NMDA] receptor subunit epsilon-4, N-methyl-D-aspartic acid
著者Simorowski, N, Furukawa, H.
登録日2010-08-12
公開日2011-05-11
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
8S90
DownloadVisualize
BU of 8s90 by Molmil
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red (C1)
分子名称: Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
著者Syrjanen, J.L, Furukawa, H.
登録日2023-03-27
公開日2023-07-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
8S8Z
DownloadVisualize
BU of 8s8z by Molmil
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
著者Syrjanen, J.L, Furukawa, H.
登録日2023-03-27
公開日2023-07-26
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
9ARE
DownloadVisualize
BU of 9are by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARF
DownloadVisualize
BU of 9arf by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in nonactive1 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-02-23
公開日2024-07-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9BIB
DownloadVisualize
BU of 9bib by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation, C1 symmetry
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor, ...
著者Chou, T.-H, Furukawa, H.
登録日2024-04-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
2QTS
DownloadVisualize
BU of 2qts by Molmil
Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ...
著者Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E.
登録日2007-08-02
公開日2007-09-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Nature, 449, 2007
7SAB
DownloadVisualize
BU of 7sab by Molmil
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
分子名称: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAD
DownloadVisualize
BU of 7sad by Molmil
Memantine-bound GluN1a-GluN2B NMDA receptors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAA
DownloadVisualize
BU of 7saa by Molmil
Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAC
DownloadVisualize
BU of 7sac by Molmil
S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
8E96
DownloadVisualize
BU of 8e96 by Molmil
Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ...
著者Kang, H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8G18
DownloadVisualize
BU of 8g18 by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
著者Regan, M.C, Furukawa, H.
登録日2023-02-01
公開日2023-03-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Acs Chem Neurosci, 14, 2023
8E97
DownloadVisualize
BU of 8e97 by Molmil
PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.19 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E94
DownloadVisualize
BU of 8e94 by Molmil
PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E93
DownloadVisualize
BU of 8e93 by Molmil
D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E99
DownloadVisualize
BU of 8e99 by Molmil
Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E92
DownloadVisualize
BU of 8e92 by Molmil
D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2022-08-26
公開日2022-12-07
最終更新日2022-12-14
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022

227111

件を2024-11-06に公開中

PDB statisticsPDBj update infoContact PDBjnumon