6X28
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![BU of 6x28 by Molmil](/molmil-images/mine/6x28) | Crystal structure of PT2243 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | (1R)-4-(3,5-difluorophenoxy)-7-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2020-05-20 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal structure of PT2243 bound to HIF2-PasB*:ARNT-PasB* complex To Be Published
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6X37
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![BU of 6x37 by Molmil](/molmil-images/mine/6x37) | Crystal structure of PT3245 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 3-fluoro-5-{[(7R)-7-hydroxy-1-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridin-4-yl]oxy}benzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2020-05-21 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of PT3245 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6X2H
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![BU of 6x2h by Molmil](/molmil-images/mine/6x2h) | Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, cis-3-({(1S)-7-[dihydroxy(trifluoromethyl)-lambda~4~-sulfanyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)cyclobutane-1-carbonitrile | 著者 | Du, X. | 登録日 | 2020-05-20 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6X3D
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![BU of 6x3d by Molmil](/molmil-images/mine/6x3d) | Crystal structure of PT3388 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | (6R,7S)-4-[(3,3-difluorocyclobutyl)oxy]-6-fluoro-1-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridin-7-ol, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2020-05-21 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of PT3388 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6X21
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![BU of 6x21 by Molmil](/molmil-images/mine/6x21) | Crystal structure of PT1673 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 1-(3-bromo-5-fluorophenoxy)-4-[(difluoromethyl)sulfonyl]-2-nitrobenzene, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2020-05-19 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Crystal structure of PT1673 bound to HIF2a-B*:ARNT-B* complex To Be Published
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1G2I
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![BU of 1g2i by Molmil](/molmil-images/mine/1g2i) | CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION | 分子名称: | PROTEASE I, SULFATE ION | 著者 | Du, X, Choi, I.-G, Kim, R, Jancarik, J, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2000-10-19 | 公開日 | 2000-11-08 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution. Proc.Natl.Acad.Sci.USA, 97, 2000
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1ILW
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![BU of 1ilw by Molmil](/molmil-images/mine/1ilw) | |
1IM5
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![BU of 1im5 by Molmil](/molmil-images/mine/1im5) | |
7D8U
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![BU of 7d8u by Molmil](/molmil-images/mine/7d8u) | Crystal structure of the C-terminal domain of pNP868R from African swine fever virus | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, GTP--RNA guanylyltransferase, ... | 著者 | Du, X, Geng, Z, Zhang, H. | 登録日 | 2020-10-10 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and Biochemical Characteristic of the Methyltransferase (MTase) Domain of RNA Capping Enzyme from African Swine Fever Virus. J.Virol., 2020
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6CZW
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![BU of 6czw by Molmil](/molmil-images/mine/6czw) | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, {2-bromo-3-(3-chloro-5-fluorophenoxy)-6-[(difluoromethyl)sulfonyl]phenyl}methanol | 著者 | Du, X. | 登録日 | 2018-04-09 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6D09
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![BU of 6d09 by Molmil](/molmil-images/mine/6d09) | Crystal structure of PT2440 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 3-{[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-2,3-dihydro-1H-1-benzothiophen-5-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2018-04-10 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6D0B
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![BU of 6d0b by Molmil](/molmil-images/mine/6d0b) | Crystal structure of PT1614 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-2-nitro-4-[(trifluoromethyl)sulfonyl]aniline | 著者 | Du, X. | 登録日 | 2018-04-10 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of PT1614 bound to HIF2a-B*:ARNT-B* complex To Be Published
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6D0C
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![BU of 6d0c by Molmil](/molmil-images/mine/6d0c) | Crystal structure of HIF2a-B*:ARNT-B* complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2018-04-10 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex To Be Published
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7W82
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![BU of 7w82 by Molmil](/molmil-images/mine/7w82) | Crystal structure of maize RDR2 | 分子名称: | RNA-dependent RNA polymerase | 著者 | Du, X, Yang, Z, Du, J. | 登録日 | 2021-12-07 | 公開日 | 2022-06-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
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7W88
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![BU of 7w88 by Molmil](/molmil-images/mine/7w88) | |
7W84
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![BU of 7w84 by Molmil](/molmil-images/mine/7w84) | |
7YHQ
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![BU of 7yhq by Molmil](/molmil-images/mine/7yhq) | |
7YHP
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![BU of 7yhp by Molmil](/molmil-images/mine/7yhp) | |
7YHO
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![BU of 7yho by Molmil](/molmil-images/mine/7yho) | |
8HIL
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![BU of 8hil by Molmil](/molmil-images/mine/8hil) | A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom | 分子名称: | DNA-dependent RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, DNA-directed RNA polymerase subunit, ... | 著者 | Du, X, Xie, G, Hu, H, Du, J. | 登録日 | 2022-11-20 | 公開日 | 2023-03-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
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6PAI
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![BU of 6pai by Molmil](/molmil-images/mine/6pai) | |
5ZWZ
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![BU of 5zwz by Molmil](/molmil-images/mine/5zwz) | |
5ZWX
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![BU of 5zwx by Molmil](/molmil-images/mine/5zwx) | |
5UFP
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![BU of 5ufp by Molmil](/molmil-images/mine/5ufp) | Crystal structure of PT2399 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 3-({(1S)-7-[(difluoromethyl)sulfonyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2017-01-05 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models. Nature, 539, 2016
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5TBM
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![BU of 5tbm by Molmil](/molmil-images/mine/5tbm) | Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2016-09-12 | 公開日 | 2016-09-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Cancer Res., 76, 2016
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