6X28

Crystal structure of PT2243 bound to HIF2a-B*:ARNT-B* complex

Summary for 6X28

• Entry DOI: 10.2210/pdb6x28/pdb
• Descriptor: Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, (1R)-4-(3,5-difluorophenoxy)-7-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol, ... (4 entities in total)
• Functional Keywords: hif2a, pas b domain, arnt, hypoxia inducible factor, epas1, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27524.04

Authors

Du, X. (deposition date: 2020-05-20, release date: 2021-05-26, Last modification date: 2023-10-18)

• Primary citation: Du, X.; Crystal structure of PT2243 bound to HIF2-PasB*:ARNT-PasB* complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)