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1IM5

Crystal Structure of Pyrazinamidase of Pyrococcus horikoshii in Complex with Zinc

Summary for 1IM5
Entry DOI10.2210/pdb1im5/pdb
Related1ILW
Descriptor180aa long hypothetical Pyrazinamidase/Nicotinamidase, ZINC ION (3 entities in total)
Functional Keywordspyrazinamidase, pyrazinamide, nicotinamidase, tuberculosis, pza resistance, drug resistance, metal ion catalysis, cysteine hydrolase, hydrolase, amidase, covalent catalysis
Biological sourcePyrococcus horikoshii
Total number of polymer chains1
Total formula weight20287.65
Authors
Du, X.,Kim, S.-H. (deposition date: 2001-05-09, release date: 2001-12-12, Last modification date: 2024-04-03)
Primary citationDu, X.,Wang, W.,Kim, R.,Yakota, H.,Nguyen, H.,Kim, S.H.
Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii.
Biochemistry, 40:14166-14172, 2001
Cited by
PubMed: 11714269
DOI: 10.1021/bi0115479
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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