6X2H

Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex

Summary for 6X2H

• Entry DOI: 10.2210/pdb6x2h/pdb
• Descriptor: Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, cis-3-({(1S)-7-[dihydroxy(trifluoromethyl)-lambda~4~-sulfanyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)cyclobutane-1-carbonitrile, ... (4 entities in total)
• Functional Keywords: hif2a, pas b domain, arnt, hypoxia inducible factor, epas1, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27591.11

Authors

Du, X. (deposition date: 2020-05-20, release date: 2021-05-26, Last modification date: 2023-10-18)

• Primary citation: Du, X.; Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)