7YHP

CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution

Summary for 7YHP

• Entry DOI: 10.2210/pdb7yhp/pdb
• EMDB information: 33835
• Descriptor: Sex-determining region Y protein,REPRESSOR OF SILENCING 1,DNA glycosylase/AP lyase ROS1, DNA (40-MER), IRON/SULFUR CLUSTER, ... (4 entities in total)
• Functional Keywords: ros1, dna glycosylase, dna demethylation, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 111242.35

Authors

Du, X.,Du, J. (deposition date: 2022-07-14, release date: 2022-11-30, Last modification date: 2024-07-03)

• Primary citation: Du, X.,Yang, Z.,Xie, G.,Wang, C.,Zhang, L.,Yan, K.,Yang, M.,Li, S.,Zhu, J.K.,Du, J.; Molecular basis of the plant ROS1-mediated active DNA demethylation.; Nat.Plants, 9:271-279, 2023; PubMed: 36624257; DOI: 10.1038/s41477-022-01322-8

Experimental method

ELECTRON MICROSCOPY (3.1 Å)