5OQ0
 
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3Q1E
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | | 著者 | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | | 登録日 | 2010-12-17 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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6R66
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | 分子名称: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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2G3X
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6R67
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | 分子名称: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R68
 | | Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | | 分子名称: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R6I
 | | Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue | | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin | | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | 登録日 | 2019-03-27 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.467 Å) | | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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1FEM
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | 分子名称: | RETINOIC ACID, RETINOL BINDING PROTEIN | | 著者 | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | 登録日 | 1994-08-29 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1FEN
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | 分子名称: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | | 著者 | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | 登録日 | 1994-08-29 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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2G4G
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1FEL
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | 分子名称: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | | 著者 | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | 登録日 | 1994-08-29 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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2G4E
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2G3Z
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4I89
 | | Crystal structure of transthyretin in complex with diflunisal at acidic pH | | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | | 著者 | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | 登録日 | 2012-12-03 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I87
 | | Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | 著者 | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | 登録日 | 2012-12-03 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I85
 | | Crystal structure of transthyretin in complex with CHF5074 at neutral pH | | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | 著者 | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | 登録日 | 2012-12-03 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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5M98
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5LL1
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2H6U
 | | Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein) | | 分子名称: | 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) | | 著者 | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | 登録日 | 2006-06-01 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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2H1X
 | | Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | 分子名称: | 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | 著者 | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | 登録日 | 2006-05-17 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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3IWV
 | | Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) | | 分子名称: | 5-hydroxyisourate hydrolase | | 著者 | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | 登録日 | 2009-09-03 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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3IWU
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | | 分子名称: | 5-hydroxyisourate hydrolase | | 著者 | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | 登録日 | 2009-09-03 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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4WO0
 | | Crystal structure of transthyretin in complex with apigenin | | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Transthyretin | | 著者 | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | 登録日 | 2014-10-15 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.339 Å) | | 主引用文献 | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNJ
 | | Crystal structure of Transthyretin-quercetin complex | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Transthyretin | | 著者 | Zanotti, G, Cianci, M, Berni, R, Folli, C. | | 登録日 | 2014-10-13 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | | 主引用文献 | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNS
 | | Crystal structure of Transthyretin complexed with pterostilbene | | 分子名称: | DIMETHYL SULFOXIDE, Pterostilbene, SULFATE ION, ... | | 著者 | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | 登録日 | 2014-10-14 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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