6SXI
 
 | | Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype) | | 分子名称: | Fab heavy chain, Fab light chain, GLYCEROL, ... | | 著者 | Taylor, G.L, Potter, J.A, Fadda, V, Patel, A.H, Owsianka, A.M, Cowtan, V.M. | | 登録日 | 2019-09-26 | | 公開日 | 2020-10-07 | | 最終更新日 | 2021-01-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design.
NPJ Vaccines, 6, 2021
|
|
2SIM
 | | THE STRUCTURES OF SALMONELLA TYPHIMURIUM LT2 NEURAMINIDASE AND ITS COMPLEX WITH A TRANSITION STATE ANALOGUE AT 1.6 ANGSTROMS RESOLUTION | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SIALIDASE | | 著者 | Taylor, G.L, Crennell, S.J, Garman, E.F, Vimr, E.R, Laver, W.G. | | 登録日 | 1994-07-15 | | 公開日 | 1994-11-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution.
J.Mol.Biol., 259, 1996
|
|
2SIL
 | | THE STRUCTURES OF SALMONELLA TYPHIMURIUM LT2 NEURAMINIDASE AND ITS COMPLEX WITH A TRANSITION STATE ANALOGUE AT 1.6 ANGSTROMS RESOLUTION | | 分子名称: | SIALIDASE | | 著者 | Taylor, G.L, Crennell, S.J, Garman, E.F, Vimr, E.R, Laver, W.G. | | 登録日 | 1994-07-13 | | 公開日 | 1994-08-31 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution.
J.Mol.Biol., 259, 1996
|
|
5F9T
 | | Crystal Structure of Streptococcus pneumoniae NanC, covalent complex with a fluorinated Neu5Ac derivative | | 分子名称: | (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, GLYCEROL, ... | | 著者 | Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. | | 登録日 | 2015-12-10 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
|
|
1W3I
 | | Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with pyruvate | | 分子名称: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, PYRUVIC ACID | | 著者 | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | | 登録日 | 2004-07-15 | | 公開日 | 2004-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
|
|
1W3N
 | | Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with D-KDG | | 分子名称: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, 3-DEOXY-D-ARABINO-HEXONIC ACID, GLYCEROL | | 著者 | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | | 登録日 | 2004-07-17 | | 公開日 | 2004-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
|
|
1W37
 | | 2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus | | 分子名称: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, SODIUM ION | | 著者 | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | | 登録日 | 2004-07-13 | | 公開日 | 2004-09-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
|
|
6ER3
 | | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose | | 分子名称: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2017-10-16 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
Nat Commun, 8, 2017
|
|
6ER4
 | | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose | | 分子名称: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2017-10-16 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
Nat Commun, 8, 2017
|
|
6ER2
 | |
4UXD
 | | 2-keto 3-deoxygluconate aldolase from Picrophilus torridus | | 分子名称: | 1,2-ETHANEDIOL, 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Priftis, A, Zaitsev, V, Reher, M, Johnsen, U, Danson, M.J, Taylor, G.L, Schoenheit, P, Crennell, S.J. | | 登録日 | 2014-08-22 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate.
Biochemistry, 57, 2018
|
|
4X47
 | | Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with Neu5Ac2en | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Anhydrosialidase, PHOSPHATE ION | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2014-12-02 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.
Nat Commun, 6, 2015
|
|
4X6K
 | | Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with Siastatin B | | 分子名称: | (2S,3R,4S,5S)-2-(acetylamino)-5-carboxy-3,4-dihydroxypiperidinium, ACETYL GROUP, Anhydrosialidase | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2014-12-08 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.
Nat Commun, 6, 2015
|
|
4X4A
 | | Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with 2,7-Anhydro-Neu5Ac | | 分子名称: | 2-ACETYLAMINO-7-(1,2-DIHYDROXY-ETHYL)-3-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCTANE-5-CARBOXYLIC ACID, ACETYL GROUP, Anhydrosialidase, ... | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2014-12-02 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.
Nat Commun, 6, 2015
|
|
4X49
 | | Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ACETYL GROUP, Anhydrosialidase, ... | | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | | 登録日 | 2014-12-02 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.
Nat Commun, 6, 2015
|
|
4XYX
 | | NanB plus Optactamide | | 分子名称: | Optactamide, PHOSPHATE ION, Sialidase B | | 著者 | Rogers, G.W, Brear, P, Yang, L, Taylor, G.L, Westwood, N.J. | | 登録日 | 2015-02-03 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB
To Be Published
|
|
1H0X
 | | Structure of Alba: an archaeal chromatin protein modulated by acetylation | | 分子名称: | DNA BINDING PROTEIN SSO10B | | 著者 | Wardleworth, B.N, Russell, R.J.M, Bell, S.D, Taylor, G.L, White, M.F. | | 登録日 | 2002-07-01 | | 公開日 | 2002-09-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of Alba: An Archaeal Chromatin Protein Modulated by Acetylation
Embo J., 21, 2002
|
|
1H0Y
 | | Structure of Alba: an archaeal chromatin protein modulated by acetylation | | 分子名称: | DNA BINDING PROTEIN SSO10B, SULFATE ION | | 著者 | Wardleworth, B.N, Russell, R.J.M, Bell, S.D, Taylor, G.L, White, M.F. | | 登録日 | 2002-07-01 | | 公開日 | 2002-09-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Alba: An Archaeal Chromatin Protein Modulated by Acetylation
Embo J., 21, 2002
|
|
4C1W
 | | Carbohydrate binding domain from Streptococcus pneumoniae NanA sialidase complexed with 3'-sialyllactose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, NEURAMINIDASE | | 著者 | Yang, L, Connaris, H, Potter, J.A, Taylor, G.L. | | 登録日 | 2013-08-14 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Prevention of Influenza by Targeting Host Receptors Using Engineered Proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5BPV
 | | Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A | | 分子名称: | Polymerase cofactor VP35 | | 著者 | Fadda, V, Cannas, V, Zinzula, L, Distinto, S, Daino, G.L, Bianco, G, Corona, A, Esposito, F, Alcaro, S, Maccioni, E, Tramontano, E, Taylor, G.L. | | 登録日 | 2015-05-28 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A
to be published
|
|
1HG3
 | | Crystal structure of tetrameric TIM from Pyrococcus woesei. | | 分子名称: | 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Walden, H, Bell, G.S, Russell, R.J.M, Siebers, B, Hensel, R, Taylor, G.L. | | 登録日 | 2000-12-12 | | 公開日 | 2001-03-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Tiny Tim: A Small, Tetrameric, Hyperthermostable Triosephosphate Isomerase
J.Mol.Biol., 306, 2001
|
|
2YA6
 | | Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Gut, H, Xu, G, Taylor, G.L, Walsh, M.A. | | 登録日 | 2011-02-18 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
|
|
2YA8
 | | Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with Oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Gut, H, Xu, G, Taylor, G.L, Walsh, M.A. | | 登録日 | 2011-02-18 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
|
|
4YW5
 | | Crystal Structure of Streptococcus pneumoniae NanC, complex with oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, GLYCEROL, ... | | 著者 | Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. | | 登録日 | 2015-03-20 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
|
|
4YW3
 | | Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with Neu5Ac2en | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, N-acetyl-alpha-neuraminic acid, ... | | 著者 | Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. | | 登録日 | 2015-03-20 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
|
|
