4X47
Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with Neu5Ac2en
Summary for 4X47
Entry DOI | 10.2210/pdb4x47/pdb |
Descriptor | Anhydrosialidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | intramolecular, trans-sialidase, sialidase, neuraminidase, neu5ac2en, dana, inhibitor, complex, hydrolase, anhydrosialidase |
Biological source | Ruminococcus gnavus ATCC 29149 |
Total number of polymer chains | 1 |
Total formula weight | 54378.83 |
Authors | Owen, C.D.,Tailford, L.E.,Taylor, G.L.,Juge, N. (deposition date: 2014-12-02, release date: 2015-07-22, Last modification date: 2024-01-10) |
Primary citation | Tailford, L.E.,Owen, C.D.,Walshaw, J.,Crost, E.H.,Hardy-Goddard, J.,Le Gall, G.,de Vos, W.M.,Taylor, G.L.,Juge, N. Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation. Nat Commun, 6:7624-7624, 2015 Cited by PubMed: 26154892DOI: 10.1038/ncomms8624 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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