4YW3

Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with Neu5Ac2en

Summary for 4YW3

Entry DOI	10.2210/pdb4yw3/pdb
Descriptor	Neuraminidase C, PHOSPHATE ION, N-acetyl-alpha-neuraminic acid, ... (6 entities in total)
Functional Keywords	sialidase, neuraminidase, beta-propeller, cbm40, hydrolase
Biological source	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Total number of polymer chains	2
Total formula weight	149238.27
Authors	Owen, C.D.,Lukacik, P.,Potter, J.A.,Walsh, M.,Taylor, G.L. (deposition date: 2015-03-20, release date: 2015-09-23, Last modification date: 2021-06-30)
Primary citation	Owen, C.D.,Lukacik, P.,Potter, J.A.,Sleator, O.,Taylor, G.L.,Walsh, M.A. Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290:27736-27748, 2015 Cited by PubMed: 26370075 DOI: 10.1074/jbc.M115.673632 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation