6ER4

Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose

Summary for 6ER4

Entry DOI	10.2210/pdb6er4/pdb
Related PRD ID	PRD_900066
Descriptor	BNR/Asp-box repeat protein, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total)
Functional Keywords	sialidase, cbm, sialic acid, sugar binding protein
Biological source	Ruminococcus gnavus ATCC 29149
Total number of polymer chains	2
Total formula weight	43746.70
Authors	Owen, C.D.,Tailford, L.E.,Taylor, G.L.,Juge, N. (deposition date: 2017-10-16, release date: 2018-05-02, Last modification date: 2024-01-17)
Primary citation	Owen, C.D.,Tailford, L.E.,Monaco, S.,Suligoj, T.,Vaux, L.,Lallement, R.,Khedri, Z.,Yu, H.,Lecointe, K.,Walshaw, J.,Tribolo, S.,Horrex, M.,Bell, A.,Chen, X.,Taylor, G.L.,Varki, A.,Angulo, J.,Juge, N. Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8:2196-2196, 2017 Cited by PubMed: 29259165 DOI: 10.1038/s41467-017-02109-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation