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3UO1
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Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-11-16
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UYR
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BU of 3uyr by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-06
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3V4U
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BU of 3v4u by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-15
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
4G59
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BU of 4g59 by Molmil
Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, M152 protein, Retinoic acid early-inducible protein 1-gamma
著者Wang, R, Natarajan, K, Margulies, D.H.
登録日2012-07-17
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion.
Proc.Natl.Acad.Sci.USA, 109, 2012
7KGK
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BU of 7kgk by Molmil
Crystal structure of synthetic nanobody (Sb16) complexes with SARS-CoV-2 receptor binding domain
分子名称: Sb16, Sybody-16, Synthetic Nanobody, ...
著者Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2020-10-16
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7KGJ
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BU of 7kgj by Molmil
Crystal structure of synthetic nanobody (Sb45) complexes with SARS-CoV-2 receptor binding domain
分子名称: Sb45, Sybody-45, Synthetic Nanobody, ...
著者Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2020-10-16
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7KLW
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BU of 7klw by Molmil
Crystal structure of synthetic nanobody (Sb45+Sb68) complexes with SARS-CoV-2 receptor binding domain
分子名称: SB45, Synthetic Nanobody, SB68, ...
著者Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2020-11-01
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
1FM5
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BU of 1fm5 by Molmil
CRYSTAL STRUCTURE OF HUMAN CD69
分子名称: EARLY ACTIVATION ANTIGEN CD69
著者Natarajan, K, Sawicki, M.W, Margulies, D.H, Mariuzza, R.A.
登録日2000-08-16
公開日2000-12-18
最終更新日2016-09-21
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
Biochemistry, 39, 2000
1B88
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V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN
分子名称: T CELL RECEPTOR V-ALPHA DOMAIN
著者Plaksin, D, Chacko, S, Navaza, J, Margulies, D.H, Padlan, E.A.
登録日1999-02-09
公開日1999-02-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing.
J.Mol.Biol., 289, 1999
1DDH
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BU of 1ddh by Molmil
MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN IMMUNODOMINANT PEPTIDE P18-I10 FROM THE HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
分子名称: BETA-2 MICROGLOBULIN, HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120, MHC CLASS I H-2DD HEAVY CHAIN
著者Li, H, Margulies, D.H, Mariuzza, R.A.
登録日1998-06-22
公開日1999-01-13
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.
J.Mol.Biol., 283, 1998
1U58
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BU of 1u58 by Molmil
Crystal structure of the murine cytomegalovirus MHC-I homolog m144
分子名称: MHC-I homolog m144, beta-2-microglobulin
著者Natarajan, K, Hicks, A, Robinson, H, Guan, R, Margulies, D.H.
登録日2004-07-27
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the murine cytomegalovirus MHC-I homolog m144.
J.Mol.Biol., 358, 2006
1P1Z
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BU of 1p1z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2Kb
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Dimasi, N, Natarajan, K, Rangjin, G, Dam, J, Margulies, D.H, Mariuzza, R.A.
登録日2003-04-14
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
3E6F
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BU of 3e6f by Molmil
MHC CLASS I H-2Dd Heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PA9, from the Human immunodeficiency virus (BaL) envelope glycoprotein 120
分子名称: BETA-2 MICROGLOBULIN, Envelope glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Wang, R, Natarajan, K, Robinson, H, Margulies, D.H.
登録日2008-08-15
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
3ECB
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BU of 3ecb by Molmil
Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human immunodeficiency virus envelope glycoprotein 120
分子名称: 1,2-ETHANEDIOL, Beta-2 microglobulin, H-2 class I histocompatibility antigen, ...
著者Natarajan, K, Wang, R, Margulies, D.H.
登録日2008-08-29
公開日2009-07-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
J.Immunol., 183, 2009
2O5N
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BU of 2o5n by Molmil
Crystal structure of a Viral Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MuHV1gpm153, ...
著者Mans, J, Natarajan, K, Robinson, H, Margulies, D.H.
登録日2006-12-06
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cellular Expression and Crystal Structure of the Murine Cytomegalovirus Major Histocompatibility Complex Class I-like Glycoprotein, m153.
J.Biol.Chem., 282, 2007
3DMM
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BU of 3dmm by Molmil
Crystal structure of the CD8 alpha beta/H-2Dd complex
分子名称: Beta-2 microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ...
著者Wang, R, Natarajan, K, Margulies, D.H.
登録日2008-07-01
公開日2009-07-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.
J.Immunol., 183, 2009
3E6H
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BU of 3e6h by Molmil
MHC CLASS I H-2Dd heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PI10, from the human immunodeficiency virus (BaL) envelope glycoprotein 120
分子名称: Envelope glycoprotein 10-residue peptide, H-2 class I histocompatibility antigen, D-D alpha chain, ...
著者Wang, R, Natarajan, K, Robinson, H, Margulies, D.H.
登録日2008-08-15
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
2MIZ
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BU of 2miz by Molmil
Structure of the m04/gp34 mouse Cytomegalovirus Immunoevasin core domain
分子名称: m04 immunoevasin
著者Sgourakis, N.G, Natarajan, K, Margulies, D.H, Bax, A.
登録日2013-12-21
公開日2014-07-16
最終更新日2014-10-22
実験手法SOLUTION NMR
主引用文献The Structure of Mouse Cytomegalovirus m04 Protein Obtained from Sparse NMR Data Reveals a Conserved Fold of the m02-m06 Viral Immune Modulator Family.
Structure, 22, 2014
3V52
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BU of 3v52 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ...
著者Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H.
登録日2011-12-15
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
7MFV
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BU of 7mfv by Molmil
Crystal structure of synthetic nanobody (Sb16)
分子名称: 1,2-ETHANEDIOL, Synthetic Nanobody #16 (Sb16)
著者Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2021-04-11
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7TUC
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BU of 7tuc by Molmil
Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022
7TUG
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BU of 7tug by Molmil
Crystal structure of Tapasin in complex with PaSta2-Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta2 Fab heavy chain, PaSta2 Fab kappa light chain, ...
著者Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022
7TUD
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Crystal structure of HLA-B*44:05 (T73C) with 6mer EEFGRC and dipeptide GL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, EEFGRC peptide, ...
著者Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022
7TUE
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BU of 7tue by Molmil
Crystal structure of Tapasin in complex with HLA-B*44:05 (T73C)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B alpha chain, ...
著者Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022
7TUF
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Crystal structure of Tapasin in complex with PaSta1-Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta1 Fab heavy chain, PaSta1 Fab kappa light chain, ...
著者Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022

 

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