2GKI
| Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity | 分子名称: | nuclease | 著者 | Kim, Y.R, Kim, J.S, Lee, S.H, Lee, W.R, Sohn, J.N, Chung, Y.C, Shim, H.K, Lee, S.C, Kwon, M.H, Kim, Y.S. | 登録日 | 2006-04-02 | 公開日 | 2006-04-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. J.Biol.Chem., 281, 2006
|
|
6O30
| Lipid A transporter MsbA from Salmonella typhimurium | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | 著者 | Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. | 登録日 | 2019-02-25 | 公開日 | 2019-06-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.47 Å) | 主引用文献 | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
|
|
2O5K
| Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor | 分子名称: | 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE, Glycogen synthase kinase-3 beta | 著者 | Shin, D, Lee, S.C, Heo, Y.S, Cho, Y.S, Kim, Y.E, Hyun, Y.L, Cho, J.M, Lee, Y.S, Ro, S. | 登録日 | 2006-12-06 | 公開日 | 2007-10-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta Bioorg.Med.Chem.Lett., 17, 2007
|
|
1WOU
| Crystal Structure of human Trp14 | 分子名称: | thioredoxin -related protein, 14 kDa | 著者 | Woo, J.R, Kim, S.J, Jeong, W, Cho, Y.H, Lee, S.C, Chung, Y.J, Rhee, S.G, Ryu, S.E. | 登録日 | 2004-08-25 | 公開日 | 2004-09-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of cellular redox regulation by human TRP14 J.Biol.Chem., 279, 2004
|
|
6BL6
| Crystallization of lipid A transporter MsbA from Salmonella typhimurium | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | 著者 | Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C. | 登録日 | 2017-11-09 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
|
|
4DIT
| |
5VN7
| Structure of bacteriorhodopsin from crystals grown at 20 deg Celcius using GlyNCOC15+4 as an LCP host lipid | 分子名称: | Bacteriorhodopsin | 著者 | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | 登録日 | 2017-04-28 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Chemically Stable Lipids for Membrane Protein Crystallization. Cryst Growth Des, 17, 2017
|
|
5VN9
| Structure of bacteriorhodopsin from crystals grown at 4 deg C using GlyNCOC15+4 as an LCP host lipid | 分子名称: | Bacteriorhodopsin | 著者 | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | 登録日 | 2017-04-28 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | 主引用文献 | Chemically Stable Lipids for Membrane Protein Crystallization. Cryst Growth Des, 17, 2017
|
|
4HYX
| Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-4 DMPC Bicelle | 分子名称: | Bacteriorhodopsin, DECANE, GLYCEROL, ... | 著者 | Lee, S, Stout, C.D, Zhang, Q. | 登録日 | 2012-11-14 | 公開日 | 2013-03-20 | 最終更新日 | 2013-05-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4HWL
| Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-7 DMPC Bicelle | 分子名称: | Bacteriorhodopsin, GLYCEROL, HEPTANE, ... | 著者 | Lee, S, Stout, C.D, Zhang, Q. | 登録日 | 2012-11-08 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4OM5
| |
4OM4
| |
7UX9
| Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | 分子名称: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | 著者 | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | 登録日 | 2022-05-05 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell, 186, 2023
|
|
3RFS
| Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | 分子名称: | Internalin B, repeat modules, Variable lymphocyte receptor B, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-04-06 | 公開日 | 2012-03-14 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3RFJ
| Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | 分子名称: | Internalin B, repeat modules, Variable lymphocyte receptor, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-04-06 | 公開日 | 2012-03-14 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
8P2W
| Structure of human SIT1 (focussed map / refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3 | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
8P2Z
| Structure of human SIT1 bound to L-pipecolate (focussed map / refinement) | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
8P30
| Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
8P2Y
| Structure of human SIT1:ACE2 complex (closed PD conformation) | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
8P31
| Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
8P2X
| Structure of human SIT1:ACE2 complex (open PD conformation) | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
|
|
6IWD
| The PTP domain of human PTPN14 in a complex with the CR3 domain of HPV18 E7 | 分子名称: | CHLORIDE ION, HPV18 E7, PHOSPHATE ION, ... | 著者 | Yun, H.-Y, Kim, S.J, Ku, B. | 登録日 | 2018-12-05 | 公開日 | 2019-07-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus. Plos Biol., 17, 2019
|
|
6TZ8
| |
6TZ7
| Crystal Structure of Aspergillus fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | 分子名称: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | 著者 | Fox III, D, Horanyi, P.S. | 登録日 | 2019-08-10 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
|
|
6TZ6
| Crystal Structure of Candida Albicans Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | 分子名称: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | 著者 | Fox III, D, Lukacs, C.M. | 登録日 | 2019-08-10 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
|
|