7JPH
| Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | 著者 | Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J. | 登録日 | 2020-08-08 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | 主引用文献 | Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nat Commun, 12, 2021
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3V4V
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yu, Y, Zhu, J, Springer, T.A. | 登録日 | 2011-12-15 | 公開日 | 2012-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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3V4P
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yu, Y, Zhu, J, Springer, T.A. | 登録日 | 2011-12-15 | 公開日 | 2012-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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5XZR
| The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b | 分子名称: | 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Li, D, Xie, J, Zhu, J, Liu, C. | 登録日 | 2017-07-13 | 公開日 | 2017-12-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment. J. Med. Chem., 60, 2017
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8G57
| Structure of nucleosome-bound Sirtuin 6 deacetylase | 分子名称: | DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ... | 著者 | Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P. | 登録日 | 2023-02-11 | 公開日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Sci Adv, 9, 2023
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4HBQ
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4HC1
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8GYD
| Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16 | 分子名称: | (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme | 著者 | Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X. | 登録日 | 2022-09-22 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library. J.Med.Chem., 66, 2023
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4HCR
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4HD9
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8GWW
| Small-molecule Allosteric Regulation Mechanism of SHP2 | 分子名称: | 2-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-5-[2,3-bis(chloranyl)phenyl]-3-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-one, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Luo, Y, Zhu, J, Yu, K, Liu, B. | 登録日 | 2022-09-17 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Small-molecule Allosteric Regulation Mechanism of SHP2 To Be Published
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4NLH
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8HWG
| D5 ATPrS-ADP-ssDNA form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWH
| Cryo-EM Structure of D5 Apo-ssDNA form | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWD
| Cryo-EM Structure of D5 ADP form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWC
| Cryo-EM Structure of D5 Apo | 分子名称: | Primase D5 | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWB
| D5 ATP-ADP-Apo-ssDNA IS2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWE
| Cryo-EM Structure of D5 ATP-ADP form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWA
| D5 ATP-ADP-Apo-ssDNA IS1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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8HWF
| Cryo-EM Structure of D5 ADP-ssDNA form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | 登録日 | 2022-12-29 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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4JHR
| An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs | 分子名称: | G-protein-signaling modulator 2 | 著者 | Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M. | 登録日 | 2013-03-05 | 公開日 | 2013-06-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs Structure, 21, 2013
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7WF6
| Crystal structure of SNX13 RGS domain | 分子名称: | CHLORIDE ION, Sorting nexin-13 | 著者 | Xu, J, Zhu, J, Liu, J. | 登録日 | 2021-12-26 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins. J.Mol.Biol., 434, 2022
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6KOE
| X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis | 分子名称: | 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | 著者 | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | 登録日 | 2019-08-09 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KOC
| X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis complexed with 3-iodo-N-oxo-2-heptyl-4-hydroxyquinoline | 分子名称: | 2-heptyl-3-iodanyl-1-oxidanyl-quinolin-4-one, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ... | 著者 | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | 登録日 | 2019-08-09 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KOB
| X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis | 分子名称: | AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, AA3-600 quinol oxidase subunit IV,Quinol oxidase subunit 4, ... | 著者 | Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J. | 登録日 | 2019-08-09 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site. Proc.Natl.Acad.Sci.USA, 117, 2020
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