7JPH

Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution

Summary for 7JPH

• Entry DOI: 10.2210/pdb7jph/pdb
• Descriptor: Envelope glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: ebola glycoprotein, viral protein
• Biological source: Ebola virus - Mayinga, Zaire, 1976 (ZEBOV); More
• Total number of polymer chains: 2
• Total formula weight: 53094.31

Authors

Chaudhary, A.,Stanfield, R.L.,Wilson, I.A.,Zhu, J. (deposition date: 2020-08-08, release date: 2021-04-07, Last modification date: 2023-10-18)

• Primary citation: He, L.,Chaudhary, A.,Lin, X.,Sou, C.,Alkutkar, T.,Kumar, S.,Ngo, T.,Kosviner, E.,Ozorowski, G.,Stanfield, R.L.,Ward, A.B.,Wilson, I.A.,Zhu, J.; Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.; Nat Commun, 12:2633-2633, 2021; PubMed: 33976149; DOI: 10.1038/s41467-021-22867-w

Experimental method

X-RAY DIFFRACTION (3.195 Å)