2FYZ
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4RZI
| Crystal structure of PhaB from Synechocystis sp. PCC 6803 | 分子名称: | 3-ketoacyl-acyl carrier protein reductase | 著者 | Xue, S, Liu, Y. | 登録日 | 2014-12-22 | 公開日 | 2015-09-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.891 Å) | 主引用文献 | Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803. Febs Lett., 589, 2015
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4XNR
| Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch | 著者 | Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R. | 登録日 | 2015-01-16 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Synthesis and applications of RNAs with position-selective labelling and mosaic composition. Nature, 522, 2015
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8X3S
| Crystal structure of human WDR5 in complex with PTEN | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, WD repeat-containing protein 5 | 著者 | Liu, Y, Huang, X, Shang, X. | 登録日 | 2023-11-14 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif. Cell Death Dis, 15, 2024
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8X3R
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5JZV
| The structure of D77G hCINAP-ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase isoenzyme 6 | 著者 | Liu, Y, Yang, Z, Yang, Y, Cai, X, Zheng, X. | 登録日 | 2016-05-17 | 公開日 | 2016-08-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth. Nat Commun, 7, 2016
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7S15
| GLP-1 receptor bound with Pfizer small molecule agonist | 分子名称: | 2-[(4-{6-[(2,4-difluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(1-ethyl-1H-imidazol-5-yl)methyl]-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor | 著者 | Liu, Y, Dias, J.M, Han, S. | 登録日 | 2021-09-01 | 公開日 | 2022-06-08 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor. J.Med.Chem., 65, 2022
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6GRC
| eukaryotic junction-resolving enzyme GEN-1 binding with Sodium | 分子名称: | DNA (5'-D(*TP*AP*CP*CP*CP*AP*CP*CP*AP*CP*CP*GP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), MAGNESIUM ION, ... | 著者 | Lilley, D.M.J, Liu, Y, Freeman, D.J. | 登録日 | 2018-06-11 | 公開日 | 2018-09-26 | 最終更新日 | 2019-02-13 | 実験手法 | X-RAY DIFFRACTION (2.452 Å) | 主引用文献 | A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1. Nucleic Acids Res., 46, 2018
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6GRD
| eukaryotic junction-resolving enzyme GEN-1 binding with Cesium | 分子名称: | CESIUM ION, DNA (5'-D(*TP*AP*CP*CP*CP*AP*CP*CP*AP*CP*CP*GP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), ... | 著者 | Lilley, D.M.J, Liu, Y, Freeman, D.J. | 登録日 | 2018-06-11 | 公開日 | 2018-09-26 | 最終更新日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1. Nucleic Acids Res., 46, 2018
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6GRB
| eukaryotic junction-resolving enzyme GEN-1 binding with Potassium | 分子名称: | DNA (5'-D(*TP*AP*CP*CP*CP*AP*CP*CP*AP*CP*CP*GP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), MAGNESIUM ION, ... | 著者 | Lilley, D.M.J, Liu, Y, Freeman, D.J. | 登録日 | 2018-06-11 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1. Nucleic Acids Res., 46, 2018
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8VCN
| GluER mutant - W66F F269Y Q293T F68Y T36E P263L | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Jeffrey, P.D, Sorigue, D.R, Liu, Y, Hyster, T.K. | 登録日 | 2023-12-14 | 公開日 | 2024-03-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Asymmetric Synthesis of alpha-Chloroamides via Photoenzymatic Hydroalkylation of Olefins. J.Am.Chem.Soc., 146, 2024
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5T5A
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6V2S
| Crystal Structure of chromodomain of MPP8 in complex with inhibitor UNC3866 | 分子名称: | M-phase phosphoprotein 8, UNC3866, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-11-25 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
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6V2R
| Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866 | 分子名称: | Chromobox protein homolog 7, UNC3866, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-11-25 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
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6V2D
| Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866 | 分子名称: | Chromodomain Y-like protein 2, UNC3866, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-11-22 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
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6UE6
| PWWP1 domain of NSD2 in complex with MR837 | 分子名称: | 4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamide, Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, De Freitas, R.F, Schapira, M, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-09-20 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. J.Med.Chem., 64, 2021
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6L0O
| WH domain of human MCM8 | 分子名称: | DNA helicase MCM8, SULFATE ION | 著者 | Liu, Y, Li, J, Liu, L, Zeng, H. | 登録日 | 2019-09-26 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Crystal structure of the winged-helix domain of MCM8. Biochem.Biophys.Res.Commun., 526, 2020
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6BPH
| Crystal structure of the chromodomain of RBBP1 | 分子名称: | AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-11-23 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of chromo barrel domain of RBBP1. Biochem. Biophys. Res. Commun., 496, 2018
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6UPL
| Structure of FACT_subnucleosome complex 2 | 分子名称: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | 著者 | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | 登録日 | 2019-10-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
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6UPK
| Structure of FACT_subnucleosome complex 1 | 分子名称: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | 著者 | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | 登録日 | 2019-10-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
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3PMG
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6MLC
| PHD6 domain of MLL3 in complex with histone H4 | 分子名称: | GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ... | 著者 | Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-09-27 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun, 10, 2019
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4QQG
| Crystal structure of an N-terminal HTATIP fragment | 分子名称: | Histone acetyltransferase KAT5, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Wernimont, A.K, Dobrovetsky, E, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and histone binding studies of the chromo barrel domain of TIP60. FEBS Lett., 592, 2018
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5IN1
| Crystal Structure of the MRG701 chromodomain | 分子名称: | 1,2-ETHANEDIOL, MRG701, SULFATE ION | 著者 | Huang, Y, Liu, Y. | 登録日 | 2016-03-07 | 公開日 | 2017-03-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants Protein Cell, 7, 2016
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5W3M
| CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle) | 分子名称: | C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ... | 著者 | Liu, Y, Dong, Y, Rossmann, M.G. | 登録日 | 2017-06-08 | 公開日 | 2017-07-12 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Antibody-induced uncoating of human rhinovirus B14. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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