6V2D

Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866

Summary for 6V2D

Entry DOI	10.2210/pdb6v2d/pdb
Related PRD ID	PRD_002208
Descriptor	Chromodomain Y-like protein 2, UNC3866, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywords	structural genomics, structural genomics consortium, sgc, gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	51448.12
Authors	Liu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2019-11-22, release date: 2019-12-25, Last modification date: 2023-10-11)
Primary citation	Dong, C.,Liu, Y.,Lyu, T.J.,Beldar, S.,Lamb, K.N.,Tempel, W.,Li, Y.,Li, Z.,James, L.I.,Qin, S.,Wang, Y.,Min, J. Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27:827-838.e7, 2020 Cited by PubMed: 32470319 DOI: 10.1016/j.chembiol.2020.05.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation