6V2R

Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866

Summary for 6V2R

Entry DOI	10.2210/pdb6v2r/pdb
Related PRD ID	PRD_002208
Descriptor	Chromobox protein homolog 7, UNC3866, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywords	structural genomics, structural genomics consortium, sgc, gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	9098.40
Authors	Liu, Y.,Tempel, W.,Walker, J.R.,Stuckey, J.I.,Dickson, B.M.,James, L.I.,Frye, S.V.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2019-11-25, release date: 2019-12-25, Last modification date: 2023-10-11)
Primary citation	Dong, C.,Liu, Y.,Lyu, T.J.,Beldar, S.,Lamb, K.N.,Tempel, W.,Li, Y.,Li, Z.,James, L.I.,Qin, S.,Wang, Y.,Min, J. Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27:827-838.e7, 2020 Cited by PubMed: 32470319 DOI: 10.1016/j.chembiol.2020.05.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation