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6V2R

Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Chromobox protein homolog 7polymer566788.81UniProt (O95931)
Pfam (PF00385)
Homo sapiens (Human)CBX7
2B
(B)
UNC3866polymer6795.01BIRD (PRD_002208)synthetic construct
3C, D, E, F, G...
(A)
UNKNOWN ATOM OR IONnon-polymer89.117Chemie (UNX)
4T, U
(A, B)
waterwater18.054Chemie (HOH)
Sequence modifications
A: 7 - 62 (UniProt: O95931)
PDBExternal DatabaseDetails
Ala 13Val 13engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight7583.8
Non-Polymers*Number of molecules17
Total formula weight1514.6
All*Total formula weight9098.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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