7E57
 
 | | Crystal structure of murine GITR-GITRL complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18, ... | | 著者 | Zhao, M, Tan, S, Fu, L, Chai, Y, Qi, J, Gao, G.F. | | 登録日 | 2021-02-18 | | 公開日 | 2021-09-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.302 Å) | | 主引用文献 | Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation.
Cell Rep, 36, 2021
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7E5N
 | | crystal structure of cis assembled TROP-2 | | 分子名称: | Tumor-associated calcium signal transducer 2 | | 著者 | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | | 登録日 | 2021-02-19 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2.
Iscience, 24, 2021
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7E5M
 | | crystal structure of trans assembled human TROP-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor-associated calcium signal transducer 2 | | 著者 | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | | 登録日 | 2021-02-19 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2.
Iscience, 24, 2021
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7W1Y
 | | Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ... | | 著者 | Li, J, Dong, J, Dang, S, Zhai, Y. | | 登録日 | 2021-11-21 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | The human pre-replication complex is an open complex.
Cell, 186, 2023
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7YE7
 | | Crystal structure of SARS-CoV-2 soluble dimeric ORF9b | | 分子名称: | N-OCTANE, ORF9b protein, nonane | | 著者 | Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F. | | 登録日 | 2022-07-05 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism.
Sci China Life Sci, 66, 2023
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7YE8
 | | Crystal structure of SARS-CoV-2 refolded dimeric ORF9b | | 分子名称: | N-OCTANE, ORF9b protein | | 著者 | Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F. | | 登録日 | 2022-07-05 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism.
Sci China Life Sci, 66, 2023
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7XNF
 | | Structure of SARS-CoV-2 antibody P2C-1F11 with GX/P2V/2017 RBD | | 分子名称: | P2C-1F11 Heavy Chain, P2C-1F11 Lambda chain, Spike protein S1 | | 著者 | Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F. | | 登録日 | 2022-04-28 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017.
Cell Rep, 41, 2022
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7XSW
 | | Structure of SARS-CoV-2 antibody S309 with GX/P2V/2017 RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Heavy Chain, S309 Lambda Chain, ... | | 著者 | Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F. | | 登録日 | 2022-05-15 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017.
Cell Rep, 41, 2022
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7W8G
 | | Cryo-EM structure of MCM double hexamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | | 著者 | Cheng, J, Li, N, Tye, B, Zhai, Y, Gao, N. | | 登録日 | 2021-12-07 | | 公開日 | 2022-04-13 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7Y3N
 | | Crystal structure of SARS-CoV receptor binding domain in complex with human antibody BIOLS56 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, ... | | 著者 | Rao, X, Chai, Y, Wu, Y, Gao, F. | | 登録日 | 2022-06-11 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7XAE
 | | Crystal strucutre of PD-L1 and 3ONJA protein | | 分子名称: | 2IC6, Programmed cell death 1 ligand 1 | | 著者 | Liu, K.F, Xu, Z.P, Han, P, Gao, G.F, Chai, Y, Tan, S.G. | | 登録日 | 2022-03-17 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | | 主引用文献 | Crystal strucutre of PD-L1 and 2IC6 protein
To Be Published
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7XQS
 | | The structure of FLA-K*00701/KP-CoV-9 | | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | | 登録日 | 2022-05-08 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides
To Be Published
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7XQT
 | | The structure of FLA-K*00701/KP-FECV-11 | | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | | 登録日 | 2022-05-08 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides
To Be Published
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7XAD
 | | Crystal strucutre of PD-L1 and DBL2_02 designed protein binder | | 分子名称: | DBL2_02 binder, Programmed cell death 1 ligand 1 | | 著者 | Liu, K.F, Xu, Z.P, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S.G. | | 登録日 | 2022-03-17 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | De novo design of protein interactions with learned surface fingerprints.
Nature, 617, 2023
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7XYQ
 | | Crystal strucutre of PD-L1 and the computationally designed DBL1_03 protein binder | | 分子名称: | ARGININE, CD274 molecule, DBL1_03 | | 著者 | Liu, K, Xu, Z, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S. | | 登録日 | 2022-06-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | De novo design of protein interactions with learned surface fingerprints.
Nature, 617, 2023
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7WVM
 | | The complex structure of PD-1 and cemiplimab | | 分子名称: | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 | | 著者 | Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy.
Front Immunol, 13, 2022
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7XQU
 | | The structure of FLA-E*00301/EM-FECV-10 | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide from Nucleoprotein | | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | | 登録日 | 2022-05-08 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides
To Be Published
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5BPE
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8HWT
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8HWS
 | | The complex structure of Omicron BA.4 RBD with BD604, S309, and S304 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab Heavy chain, BD-604 Fab Light chain, ... | | 著者 | He, Q.W, Xu, Z.P, Xie, Y.F. | | 登録日 | 2023-01-02 | | 公開日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | | 主引用文献 | An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB.
Cell Rep Med, 4, 2023
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2G9T
 | | Crystal structure of the SARS coronavirus nsp10 at 2.1A | | 分子名称: | ZINC ION, orf1a polyprotein | | 著者 | Su, D, Lou, Z, Yang, H, Sun, F, Rao, Z. | | 登録日 | 2006-03-07 | | 公開日 | 2006-08-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
J.Virol., 80, 2006
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8H77
 | | Hsp90-AhR-p23-XAP2 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | | 著者 | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | | 登録日 | 2022-10-19 | | 公開日 | 2023-01-04 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
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4Y9L
 | | Crystal Structure of Caenorhabditis elegans ACDH-11 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Protein ACDH-11, isoform b | | 著者 | Li, Z.J, Zhai, Y.J, Zhang, K, Sun, F. | | 登録日 | 2015-02-17 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids
Cell, 161, 2015
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8XFZ
 | | The structure of HLA-A/L1-2 | | 分子名称: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | | 著者 | Zhang, J.N, Yue, C, Liu, J. | | 登録日 | 2023-12-14 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
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8XKE
 | | The structure of HLA-A/14-3-D | | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain | | 著者 | Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y. | | 登録日 | 2023-12-23 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
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