7XAD

Crystal strucutre of PD-L1 and DBL2_02 designed protein binder

Summary for 7XAD

• Entry DOI: 10.2210/pdb7xad/pdb
• Descriptor: Programmed cell death 1 ligand 1, DBL2_02 binder (2 entities in total)
• Functional Keywords: pd-l1, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 157567.24

Authors

Liu, K.F.,Xu, Z.P.,Han, P.,Pacesa, M.,Gao, G.F.,Chai, Y.,Tan, S.G. (deposition date: 2022-03-17, release date: 2023-04-12, Last modification date: 2023-11-29)

• Primary citation: Gainza, P.,Wehrle, S.,Van Hall-Beauvais, A.,Marchand, A.,Scheck, A.,Harteveld, Z.,Buckley, S.,Ni, D.,Tan, S.,Sverrisson, F.,Goverde, C.,Turelli, P.,Raclot, C.,Teslenko, A.,Pacesa, M.,Rosset, S.,Georgeon, S.,Marsden, J.,Petruzzella, A.,Liu, K.,Xu, Z.,Chai, Y.,Han, P.,Gao, G.F.,Oricchio, E.,Fierz, B.,Trono, D.,Stahlberg, H.,Bronstein, M.,Correia, B.E.; De novo design of protein interactions with learned surface fingerprints.; Nature, 617:176-184, 2023; PubMed: 37100904; DOI: 10.1038/s41586-023-05993-x

Experimental method

X-RAY DIFFRACTION (3 Å)