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7XYX
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BU of 7xyx by Molmil
Crystal structure of ZYG11B bound to CFLH degron
分子名称: Protein zyg-11 homolog B
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYS
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BU of 7xys by Molmil
Crystal structure of ZER1 bound to SFLH degron
分子名称: Protein zer-1 homolog
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYU
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BU of 7xyu by Molmil
Crystal structure of ZER1 bound to TFLH degron
分子名称: Protein zer-1 homolog
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
4WSI
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BU of 4wsi by Molmil
Crystal Structure of PALS1/Crb complex
分子名称: MAGUK p55 subfamily member 5, Protein crumbs
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-10-28
公開日2014-11-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
1SMF
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BU of 1smf by Molmil
Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor
分子名称: BOWMAN-BIRK TYPE TRYPSIN INHIBITOR, CALCIUM ION, TRYPSIN
著者Huang, Q, Li, Y, Zhang, S, Liu, S, Tang, Y, Qi, C.
登録日1992-10-24
公開日1994-07-31
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Studies on an artificial trypsin inhibitor peptide derived from the mung bean trypsin inhibitor: chemical synthesis, refolding, and crystallographic analysis of its complex with trypsin.
J.Biochem.(Tokyo), 116, 1994
4ZRK
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BU of 4zrk by Molmil
Merlin-FERM and Lats1 complex
分子名称: Merlin, Serine/threonine-protein kinase LATS1
著者Lin, Z, Li, Y, Wei, Z, Zhang, M.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.316 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
7BT6
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BU of 7bt6 by Molmil
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Li, Y, Wilson, D.M.
登録日2020-03-31
公開日2020-10-28
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel.
Nat Commun, 11, 2020
7BTB
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BU of 7btb by Molmil
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Li, Y, Wilson, D.M.
登録日2020-04-01
公開日2020-10-28
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel.
Nat Commun, 11, 2020
1TMM
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BU of 1tmm by Molmil
Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-HYDROXYMETHYLPTERIN, ACETATE ION, ...
著者Blaszczyk, J, Li, Y, Wu, Y, Shi, G, Ji, X, Yan, H.
登録日2004-06-10
公開日2005-06-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
Biochemistry, 44, 2005
1NBY
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BU of 1nby by Molmil
Crystal Structure of HyHEL-63 complexed with HEL mutant K96A
分子名称: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
著者Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J.
登録日2002-12-04
公開日2003-04-01
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
1NBZ
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BU of 1nbz by Molmil
Crystal Structure of HyHEL-63 complexed with HEL mutant K97A
分子名称: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
著者Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J.
登録日2002-12-04
公開日2003-04-01
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
8JYZ
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BU of 8jyz by Molmil
Cryo-EM structure of RCD-1 pore from Neurospora crassa
分子名称: Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2
著者Hou, Y.J, Sun, Q, Li, Y, Ding, J.
登録日2023-07-04
公開日2024-05-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
7XRB
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BU of 7xrb by Molmil
human STK19 dimer
分子名称: CHLORIDE ION, Isoform 2 of Serine/threonine-protein kinase 19, SULFATE ION
著者Sun, Q, Li, Y.
登録日2022-05-10
公開日2023-06-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献human STK19 dimer
To Be Published
2IPA
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BU of 2ipa by Molmil
solution structure of Trx-ArsC complex
分子名称: Protein arsC, Thioredoxin
著者Jin, C, Hu, Y, Li, Y, Zhang, X.
登録日2006-10-12
公開日2007-02-13
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J.Biol.Chem., 282, 2007
6ZD7
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BU of 6zd7 by Molmil
Crystal structure of YTHDC1 T379V mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
4NQJ
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BU of 4nqj by Molmil
Structure of coiled-coil domain
分子名称: DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69
著者Yang, M, Li, Y.
登録日2013-11-25
公開日2014-05-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Structural insights into the TRIM family of ubiquitin E3 ligases.
Cell Res., 24, 2014
3E5M
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BU of 3e5m by Molmil
Crystal structure of the HSCARG Y81A mutant
分子名称: NmrA-like family domain-containing protein 1
著者Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X.
登録日2008-08-14
公開日2009-05-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献NADPH is an allosteric regulator of HSCARG
J.Mol.Biol., 387, 2009
3DXF
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BU of 3dxf by Molmil
Crystal structure of the HSCARG R37A mutant
分子名称: NmrA-like family domain-containing protein 1
著者Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X.
登録日2008-07-24
公開日2009-05-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献NADPH is an allosteric regulator of HSCARG
J.Mol.Biol., 387, 2009
6P05
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BU of 6p05 by Molmil
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27
分子名称: Bromodomain-containing protein 4, GLYCEROL, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide
著者Ratia, K.M, Xiong, R, Li, Y, Zhao, J, Gutgesell, L.M, Shen, Z, Dye, K, Dubrovyskyii, O, Zhao, H, Huang, F, Tonetti, D.A, Thatcher, G.R.
登録日2019-05-16
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
J.Med.Chem., 63, 2020
5YYF
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BU of 5yyf by Molmil
Crystal structure of AF9 YEATS domain in complex with a peptide inhibitor "PHQ-H3(Q5-K9)" modified at K9 with 2-furancarboyl group
分子名称: 2-FUROIC ACID, Peptide inhibitor PHQ-H3(Q5-K9), Protein AF-9, ...
著者Li, Y, Li, H.
登録日2017-12-09
公開日2018-11-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking.
Nat. Chem. Biol., 14, 2018
5GPP
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BU of 5gpp by Molmil
Crystal structure of zebrafish ASC PYD domain
分子名称: ACETATE ION, Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, ...
著者Jin, T, Li, Y.
登録日2016-08-04
公開日2017-08-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional and structural characterization of zebrafish ASC.
FEBS J., 285, 2018
5GPQ
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BU of 5gpq by Molmil
Crystal Structure of zebrafish ASC CARD Domain
分子名称: CITRIC ACID, Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T, Li, Y.
登録日2016-08-04
公開日2017-08-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional and structural characterization of zebrafish ASC.
FEBS J., 285, 2018
3HSZ
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BU of 3hsz by Molmil
Crystal structure of E. coli HPPK(F123A)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ...
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-06-11
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
3HT0
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BU of 3ht0 by Molmil
Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP
分子名称: CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, HPPK, ...
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-06-11
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
3HSG
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BU of 3hsg by Molmil
Crystal structure of E. coli HPPK(Y53A) in complex with MgAMPCPP
分子名称: ACETATE ION, CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-06-10
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published

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件を2024-07-10に公開中

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