6ZD7

Crystal structure of YTHDC1 T379V mutant complex with m6A

Summary for 6ZD7

• Entry DOI: 10.2210/pdb6zd7/pdb
• Descriptor: YTH domain containing 1, SULFATE ION, N-methyladenosine, ... (4 entities in total)
• Functional Keywords: ythdc1, m6a, complex, inhibitor, rna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 43165.35

Authors

Bedi, R.K.,Li, Y.,Caflisch, A. (deposition date: 2020-06-13, release date: 2021-01-13, Last modification date: 2024-01-24)

• Primary citation: Li, Y.,Bedi, R.K.,Wiedmer, L.,Sun, X.,Huang, D.,Caflisch, A.; Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.; J Chem Theory Comput, 17:1240-1249, 2021; PubMed: 33472367; DOI: 10.1021/acs.jctc.0c01136

Experimental method

X-RAY DIFFRACTION (1.75 Å)