4P9M
 
 | | Crystal structure of 8ANC195 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2014-04-04 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
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4P72
 | | PheRS in complex with compound 2a | | 分子名称: | 2-{3-[(4-chloropyridin-2-yl)amino]phenoxy}-N-methylacetamide, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit | | 著者 | Ferguson, A.D. | | 登録日 | 2014-03-25 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.
J.Biol.Chem., 289, 2014
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6I9J
 | | Human transforming growth factor beta2 in a tetragonal crystal form | | 分子名称: | Transforming growth factor beta-2 proprotein | | 著者 | Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T. | | 登録日 | 2018-11-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
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8LPR
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3IKA
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4PX6
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3IHR
 | | Crystal Structure of Uch37 | | 分子名称: | FORMIC ACID, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2009-07-30 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural characterization of human Uch37.
Proteins, 80, 2012
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4QNB
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4R73
 | | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (endogenous glucose-6-phosphate and mannose-6-phosphate bound) | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, ABC-type Fe3+ transport system, ... | | 著者 | Calmettes, C, Tang, C, Sit, B, Moraes, T.F. | | 登録日 | 2014-08-26 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
Plos Pathog., 11, 2015
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4QQ1
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4R72
 | | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (apo form) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ABC-type Fe3+ transport system, periplasmic component, ... | | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | | 登録日 | 2014-08-26 | | 公開日 | 2015-08-12 | | 最終更新日 | 2015-09-02 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
Plos Pathog., 11, 2015
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4R26
 | | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | | 著者 | Garces, F, Kong, L, Wilson, I.A. | | 登録日 | 2014-08-08 | | 公開日 | 2014-10-08 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.4969 Å) | | 主引用文献 | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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4R2G
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4QYK
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4R75
 | | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous sedoheptulose-7-phosphate bound) | | 分子名称: | 1-C-(hydroxymethyl)-6-O-phosphono-beta-D-altrofuranose, ABC-type Fe3+ transport system, periplasmic component, ... | | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | | 登録日 | 2014-08-26 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.278 Å) | | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
Plos Pathog., 11, 2015
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4R74
 | | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous fructose-6-phosphate bound) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-O-phosphono-beta-D-fructofuranose, ABC-type Fe3+ transport system, ... | | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | | 登録日 | 2014-08-26 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
Plos Pathog., 11, 2015
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4RQQ
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4RX8
 | | SYK Catalytic Domain Complexed with a Potent Triazine Inhibitor2 | | 分子名称: | 3-{[(1R,2S)-2-aminocyclohexyl]amino}-5-(1H-indol-7-ylamino)-1,2,4-triazine-6-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK | | 著者 | Lee, C.C. | | 登録日 | 2014-12-09 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Discovery and profiling of a selective and efficacious syk inhibitor.
J.Med.Chem., 58, 2015
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4RX7
 | | SYK Catalytic Domain Complexed with a Potent Triazine Inhibitor | | 分子名称: | 3-{[(1R,2S)-2-aminocyclohexyl]amino}-5-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide, FORMIC ACID, GLYCEROL, ... | | 著者 | Lee, C.C. | | 登録日 | 2014-12-09 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery and profiling of a selective and efficacious syk inhibitor.
J.Med.Chem., 58, 2015
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4RX9
 | | SYK Catalytic Domain Complexed with a Potent Pyrimidine Inhibitor | | 分子名称: | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK | | 著者 | Lee, C.C. | | 登録日 | 2014-12-09 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery and profiling of a selective and efficacious syk inhibitor.
J.Med.Chem., 58, 2015
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3I28
 | | Crystal Structure of soluble epoxide Hydrolase | | 分子名称: | 4-cyano-N-{(3S)-3-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]propyl}benzamide, Epoxide hydrolase 2 | | 著者 | Farrow, N.A. | | 登録日 | 2009-06-29 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.
J.Med.Chem., 52, 2009
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4TY1
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4TOY
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4RPV
 | | co-crystal structure of Pim1 with compound 3 | | 分子名称: | (3S)-1-{6-[5-(2,6-difluorophenyl)-2H-indazol-3-yl]pyrazin-2-yl}piperidin-3-amine, Serine/threonine-protein kinase pim-1 | | 著者 | Huang, X. | | 登録日 | 2014-10-31 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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3I1Y
 | | Crystal Structure of soluble epoxide Hydrolase | | 分子名称: | Epoxide hydrolase 2, N-(3,3-diphenylpropyl)pyridine-3-carboxamide | | 著者 | Farrow, N.A. | | 登録日 | 2009-06-28 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.469 Å) | | 主引用文献 | Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.
J.Med.Chem., 52, 2009
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