4E7U
 
 | | The structure of T3R3 bovine insulin | | 分子名称: | Insulin A chain, Insulin B chain, THIOCYANATE ION, ... | | 著者 | Harris, P, Frankaer, C.G, Knudsen, M.V. | | 登録日 | 2012-03-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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6HXM
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6HXO
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6HXI
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6HXH
 | | Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ... | | 著者 | Verstraete, K, Verschueren, K. | | 登録日 | 2018-10-17 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
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6HXL
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6HXP
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6HXN
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6HXQ
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6HXJ
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6HXK
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4K7D
 | | Crystal Structure of Parkin C-terminal RING domains | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, MALONATE ION, ... | | 著者 | Sauve, V, Trempe, J.-F, Menade, M, Gehring, K. | | 登録日 | 2013-04-17 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
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3NMQ
 | | Hsp90b N-terminal domain in complex with EC44, a pyrrolo-pyrimidine methoxypyridine inhibitor | | 分子名称: | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-beta | | 著者 | Arndt, J.W, Yun, T.J, Harning, E.K, Giza, K, Rabah, D, Li, P, Luchetti, D, Shi, J, Manning, A, Kehry, M.R. | | 登録日 | 2010-06-22 | | 公開日 | 2010-12-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity.
J.Immunol., 186, 2011
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4K95
 | | Crystal Structure of Parkin | | 分子名称: | E3 ubiquitin-protein ligase parkin, ZINC ION | | 著者 | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | | 登録日 | 2013-04-19 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (6.499 Å) | | 主引用文献 | Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
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8R74
 | | Galectin-1 in complex with thiogalactoside derivative | | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(2-oxidanyl-1,3-thiazol-4-yl)-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-1 | | 著者 | Hakansson, M, Diehl, C, Peterson, K, Zetterberg, F, Nilsson, U. | | 登録日 | 2023-11-23 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer.
J.Med.Chem., 67, 2024
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3I9G
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6BXI
 | | X-ray crystal structure of NDR1 kinase domain | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase 38 | | 著者 | Xiong, S, Sicheri, F. | | 登録日 | 2017-12-18 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Structure, 26, 2018
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5JPE
 | | Yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans | | 分子名称: | CITRATE ANION, GLYCEROL, Serine/threonine-protein phosphatase | | 著者 | Choy, M.S, Chen, E.H, Peti, W, Page, R. | | 登録日 | 2016-05-03 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.611 Å) | | 主引用文献 | Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
Mbio, 7, 2016
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8DS5
 | | X-ray structure of the MK5890 Fab - CD27 antibody-antigen complex | | 分子名称: | CADMIUM ION, CD27 antigen, MK-5890 Fab heavy chain, ... | | 著者 | Fischmann, T.O. | | 登録日 | 2022-07-21 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.926 Å) | | 主引用文献 | Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy.
J Immunother Cancer, 10, 2022
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5JPF
 | | Serine/Threonine phosphatase Z1 (Candida albicans) binds to inhibitor microcystin-LR | | 分子名称: | MALONATE ION, MANGANESE (II) ION, Microcystin-LR, ... | | 著者 | Choy, M.S, Chen, E.H, Peti, W, Page, R. | | 登録日 | 2016-05-03 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.39929724 Å) | | 主引用文献 | Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
Mbio, 7, 2016
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3QDD
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5AIW
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5FEH
 | | Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody | | 分子名称: | 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ... | | 著者 | Murrell, S, Wilson, I.A. | | 登録日 | 2015-12-17 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
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5G3X
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5G0Z
 | | Structure of native granulovirus polyhedrin determined using an X-ray free-electron laser | | 分子名称: | GRANULIN | | 著者 | Gati, C, Bunker, R.D, Oberthur, D, Metcalf, P, Henry, C. | | 登録日 | 2016-03-23 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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