3I9G

Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate

Summary for 3I9G

Entry DOI	10.2210/pdb3i9g/pdb
Descriptor	Sonepcizumab antibody Fab fragment, heavy chain, Sonepcizumab antibody Fab fragment, light chain, CALCIUM ION, ... (6 entities in total)
Functional Keywords	antibody, fab, sphingosine-1-phosphate, calcium, immunoglobin, igg, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	48051.25
Authors	Huxford, T. (deposition date: 2009-07-10, release date: 2009-09-29, Last modification date: 2011-07-13)
Primary citation	Wojciak, J.M.,Zhu, N.,Schuerenberg, K.T.,Moreno, K.,Shestowsky, W.S.,Hiraiwa, M.,Sabbadini, R.,Huxford, T. The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc.Natl.Acad.Sci.USA, 106:17717-17722, 2009 Cited by PubMed: 19815502 DOI: 10.1073/pnas.0906153106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation