3Q33
 
 | | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, HISTONE H3, ... | | 著者 | Tang, Y, Yuan, H, Meeth, K, Marmorstein, R. | | 登録日 | 2010-12-21 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
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3FPT
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8F73
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6HXA
 | | AntI from P. luminescens catalyses terminal polyketide shortening in the biosynthesis of anthraquinones | | 分子名称: | AntI, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | 著者 | Zhou, Q, Braeuer, A, Grammbitter, G, Schmalhofer, M, Saura, P, Adihou, H, Kaila, V.R.I, Groll, M, Bode, H. | | 登録日 | 2018-10-16 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Molecular mechanism of polyketide shortening in anthraquinone biosynthesis ofPhotorhabdus luminescens.
Chem Sci, 10, 2019
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8FWP
 | | Crystal Structure of CDC10 - CDC3 heterocomplex from Saccharomyces cerevisiae | | 分子名称: | Cell division control protein 10, Cell division control protein 3, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Silva, R.M, Leonardo, D.A, Pereira, H.M, Garratt, R.C. | | 登録日 | 2023-01-23 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly.
J.Struct.Biol., 215, 2023
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6Q7M
 | | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | | 著者 | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | | 登録日 | 2018-12-13 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-02-19 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
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6Q7L
 | | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | | 著者 | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | | 登録日 | 2018-12-13 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-02-19 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
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2PJL
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2AXK
 | | Solution structure of discrepin, a scorpion venom toxin blocking K+ channels. | | 分子名称: | discrepin | | 著者 | Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M. | | 登録日 | 2005-09-05 | | 公開日 | 2006-06-20 | | 最終更新日 | 2019-12-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry, 45, 2006
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5OA4
 | | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ_V72I mutant in complex with 4-methoxycyclopeptin (1) | | 分子名称: | (3S)-3-(4-methoxybenzyl)-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Groll, M, Braeuer, A, Kaila, V.R.I. | | 登録日 | 2017-06-20 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.
Nat Commun, 9, 2018
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3TXO
 | | PKC eta kinase in complex with a naphthyridine | | 分子名称: | 2-methyl-N~1~-[3-(pyridin-4-yl)-2,6-naphthyridin-1-yl]propane-1,2-diamine, Protein kinase C eta type | | 著者 | Stark, W, Rummel, G, Cowan-Jacob, S.W. | | 登録日 | 2011-09-23 | | 公開日 | 2011-11-30 | | 最終更新日 | 2011-12-07 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | 2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes.
Bioorg.Med.Chem.Lett., 21, 2011
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3GGW
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3CS9
 | | Human ABL kinase in complex with nilotinib | | 分子名称: | Nilotinib, Proto-oncogene tyrosine-protein kinase ABL1 | | 著者 | Cowan-Jacob, S.W, Fendrich, G, Manley, P, Liebetanz, J, Fabbro, D. | | 登録日 | 2008-04-09 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
Cancer Cell, 7, 2005
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6EOZ
 | | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ_V72K mutant in complex with cyclopeptin (1b) | | 分子名称: | 2-OXOGLUTARIC ACID, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, NICKEL (II) ION, ... | | 著者 | Groll, M, Braeuer, A, Kaila, V.R.I. | | 登録日 | 2017-10-10 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.
Nat Commun, 9, 2018
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8EFU
 | | a22L prion fibril | | 分子名称: | Major prion protein | | 著者 | Hoyt, F, Caughey, B. | | 登録日 | 2022-09-09 | | 公開日 | 2022-11-02 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM of prion strains from the same genotype of host identifies conformational determinants.
Plos Pathog., 18, 2022
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4C9T
 | | BACTERIAL CHALCONE ISOMERASE IN open CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SelenoMet derivative | | 分子名称: | CHALCONE ISOMERASE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Thomsen, M, Palm, G.J, Hinrichs, W. | | 登録日 | 2013-10-03 | | 公開日 | 2014-10-22 | | 最終更新日 | 2015-04-22 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structure and Catalytic Mechanism of the Evolutionarily Unique Bacterial Chalcone Isomerase
Acta Crystallogr.,Sect.D, 71, 2015
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4C9S
 | | BACTERIAL CHALCONE ISOMERASE IN open CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | | 分子名称: | CHALCONE ISOMERASE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Thomsen, M, Palm, G.J, Hinrichs, W. | | 登録日 | 2013-10-03 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and Catalytic Mechanism of the Evolutionarily Unique Bacterial Chalcone Isomerase
Acta Crystallogr.,Sect.D, 71, 2015
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6HLF
 | | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant - K32A | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, R-specific alcohol dehydrogenase | | 著者 | Hermann, J, Nowotny, P, Schneider, S, Hekmat, D, Weuster-Botz, D. | | 登録日 | 2018-09-11 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Rational Crystal Contact Engineering of Lactobacillus brevis Alcohol Dehydrogenase To Promote Technical Protein Crystallization
Cryst.Growth Des., 2019
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6I2I
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6I4B
 | | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with 3-Hydroxy-1-methyl-5-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole-4-carboxylic acid | | 分子名称: | 1-methyl-3-oxidanyl-5-[[3-(trifluoromethyl)phenoxy]methyl]pyrazole-4-carboxylic acid, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Goyal, P, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S. | | 登録日 | 2018-11-09 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Eur J Med Chem, 163, 2018
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6I55
 | | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with N-(2,2-Diphenylethyl)-4-hydroxy-1,2,5-thiadiazole-3-carboxamide | | 分子名称: | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, N-(2,2-Diphenylethyl)-4-hydroxy-1,2,5-thiadiazole-3-carboxamide, ... | | 著者 | Goyal, P, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S. | | 登録日 | 2018-11-12 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Eur J Med Chem, 163, 2018
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6Y3X
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5VDR
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5VDP
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5VDO
 | | Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP | | 分子名称: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Byrnes, L.J, Hall, J.D. | | 登録日 | 2017-04-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.218 Å) | | 主引用文献 | The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
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