6I2I

Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)

Summary for 6I2I

Entry DOI	10.2210/pdb6i2i/pdb
EMDB information	0331
Descriptor	Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	microtubule, tubulin, hela, eml, structural protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	101868.98
Authors	Atherton, J.M.,Moores, C.A. (deposition date: 2018-11-01, release date: 2019-08-28, Last modification date: 2024-05-15)
Primary citation	Adib, R.,Montgomery, J.M.,Atherton, J.,O'Regan, L.,Richards, M.W.,Straatman, K.R.,Roth, D.,Straube, A.,Bayliss, R.,Moores, C.A.,Fry, A.M. Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression. Sci.Signal., 12:-, 2019 Cited by PubMed: 31409757 DOI: 10.1126/scisignal.aaw2939 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation