6I2I
Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)
Summary for 6I2I
Entry DOI | 10.2210/pdb6i2i/pdb |
EMDB information | 0331 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | microtubule, tubulin, hela, eml, structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 101868.98 |
Authors | Atherton, J.M.,Moores, C.A. (deposition date: 2018-11-01, release date: 2019-08-28, Last modification date: 2024-05-15) |
Primary citation | Adib, R.,Montgomery, J.M.,Atherton, J.,O'Regan, L.,Richards, M.W.,Straatman, K.R.,Roth, D.,Straube, A.,Bayliss, R.,Moores, C.A.,Fry, A.M. Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression. Sci.Signal., 12:-, 2019 Cited by PubMed: 31409757DOI: 10.1126/scisignal.aaw2939 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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