4JEB
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![BU of 4jeb by Molmil](/molmil-images/mine/4jeb) | Crystal structure of an engineered RIDC1 tetramer with four interfacial disulfide bonds and four three-coordinate Zn(II) sites | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, soluble cytochrome b562 | 著者 | Tezcan, F.A, Medina-Morales, A.M, Perez, A, Brodin, J.D. | 登録日 | 2013-02-26 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | In Vitro and Cellular Self-Assembly of a Zn-Binding Protein Cryptand via Templated Disulfide Bonds. J.Am.Chem.Soc., 135, 2013
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4JEA
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![BU of 4jea by Molmil](/molmil-images/mine/4jea) | Crystal structure of an engineered Zn-RIDC1 construct with four interfacial disulfide bonds | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ZINC ION, ... | 著者 | Tezcan, F.A, Medina-Morales, A.M, Perez, A, Brodin, J.D. | 登録日 | 2013-02-26 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | In Vitro and Cellular Self-Assembly of a Zn-Binding Protein Cryptand via Templated Disulfide Bonds. J.Am.Chem.Soc., 135, 2013
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4JE9
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![BU of 4je9 by Molmil](/molmil-images/mine/4je9) | Crystal structure of an engineered metal-free RIDC1 construct with four interfacial disulfide bonds | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562 | 著者 | Tezcan, F.A, Medina-Morales, A.M, Perez, A, Brodin, J.D. | 登録日 | 2013-02-26 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | In Vitro and Cellular Self-Assembly of a Zn-Binding Protein Cryptand via Templated Disulfide Bonds. J.Am.Chem.Soc., 135, 2013
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5HHX
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5HI5
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![BU of 5hi5 by Molmil](/molmil-images/mine/5hi5) | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | 分子名称: | (4S,20R)-7-chloro-N-methyl-4-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-3,18-dioxo-2,19-diazatetracyclo[20.2.2.1~6,10~.1~11,15~]octacosa-1(24),6(28),7,9,11(27),12,14,22,25-nonaene-20-carboxamide, CAT-2000 FAB heavy chain, CAT-2000 light chain, ... | 著者 | Liu, S. | 登録日 | 2016-01-11 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep, 6, 2016
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6C8Z
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![BU of 6c8z by Molmil](/molmil-images/mine/6c8z) | Last common ancestor of ADP-dependent phosphofructokinases from Methanosarcinales | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADP-dependent phosphofructokinase, MAGNESIUM ION, ... | 著者 | Castro-Fernandez, V, Gonzalez-Ordenes, F, Munoz, S, Fuentes, N, Leonardo, D, Fuentealba, M, Herrera-Morande, A, Maturana, P, Villalobos, P, Garratt, R. | 登録日 | 2018-01-25 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | ADP-Dependent Kinases From the Archaeal OrderMethanosarcinalesAdapt to Salt by a Non-canonical Evolutionarily Conserved Strategy. Front Microbiol, 9, 2018
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5HI4
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![BU of 5hi4 by Molmil](/molmil-images/mine/5hi4) | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | 分子名称: | (9'S,17'R)-6'-chloro-N-methyl-9'-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-10',19'-dioxo-2'-oxa-11',18'-diazaspiro[cyclopentane-1,21'-tetracyclo[20.2.2.2~12,15~.1~3,7~]nonacosane]-1'(24'),3'(29'),4',6',12',14',22',25',27'-nonaene-17'-carboxamide, CAT-2000 FAB heavy chain, CAT-2000 FAB light chain, ... | 著者 | Liu, S. | 登録日 | 2016-01-11 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep, 6, 2016
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5HHV
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5HI3
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6F60
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![BU of 6f60 by Molmil](/molmil-images/mine/6f60) | The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand | 分子名称: | Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound | 著者 | Merlino, A, Ferraro, G. | 登録日 | 2017-12-04 | 公開日 | 2018-04-25 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules. Inorg Chem, 57, 2018
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1B0B
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![BU of 1b0b by Molmil](/molmil-images/mine/1b0b) | HEMOGLOBIN I FROM THE CLAM LUCINA PECTINATA, CYANIDE COMPLEX AT 100 KELVIN | 分子名称: | CYANIDE ION, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Rosano, C, Rizzi, M, Ascenzi, P, Bolognesi, M. | 登録日 | 1998-11-06 | 公開日 | 2000-02-18 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: an x-ray crystallographic study. Biophys.J., 77, 1999
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6VVU
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![BU of 6vvu by Molmil](/molmil-images/mine/6vvu) | Anti-Tryptase fab E104.v1 bound to tryptase | 分子名称: | CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ... | 著者 | Ultsch, M, Koerber, J.T. | 登録日 | 2020-02-18 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge. Nat Commun, 11, 2020
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5CKA
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![BU of 5cka by Molmil](/molmil-images/mine/5cka) | Human beta-2 microglobulin double mutant W60G-N83V | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-15 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6, 2016
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5CKG
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![BU of 5ckg by Molmil](/molmil-images/mine/5ckg) | Human beta-2 microglobulin mutant V85E | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-15 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6, 2016
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5CFH
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5JQT
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![BU of 5jqt by Molmil](/molmil-images/mine/5jqt) | Crystal structure of human carbonic anhydrase II in complex with Benzoxaborole at pH 7.4 | 分子名称: | 1,1-dihydroxy-1,3-dihydro-2,1-benzoxaborol-1-ium, 2,1-benzoxaborol-1(3H)-ol, 4-(HYDROXYMERCURY)BENZOIC ACID, ... | 著者 | Alterio, V, Esposito, D, Di Fiore, A, De Simone, G. | 登録日 | 2016-05-05 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Benzoxaborole as a new chemotype for carbonic anhydrase inhibition. Chem.Commun.(Camb.), 52, 2016
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5JQ0
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![BU of 5jq0 by Molmil](/molmil-images/mine/5jq0) | Crystal structure of human carbonic anhydrase II in complex with Benzoxaborole at pH=8.7 | 分子名称: | 1,1-dihydroxy-1,3-dihydro-2,1-benzoxaborol-1-ium, Carbonic anhydrase 2, ZINC ION | 著者 | Alterio, V, Esposito, D, Di Fiore, A, De Simone, G. | 登録日 | 2016-05-04 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Benzoxaborole as a new chemotype for carbonic anhydrase inhibition. Chem.Commun.(Camb.), 52, 2016
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5C27
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![BU of 5c27 by Molmil](/molmil-images/mine/5c27) | Crystal structure of SYK in complex with compound 2 | 分子名称: | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-N-[4-(methylcarbamoyl)phenyl]benzamide, GLU-VAL-TYR-GLU-SER, GLYCEROL, ... | 著者 | Han, S, Chang, J. | 登録日 | 2015-06-15 | 公開日 | 2015-10-07 | 最終更新日 | 2016-02-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP). Chemmedchem, 11, 2016
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5C26
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![BU of 5c26 by Molmil](/molmil-images/mine/5c26) | Crystal structure of SYK in complex with compound 1 | 分子名称: | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide, GLU-VAL-PTR-GLU-SER-PRO, Tyrosine-protein kinase SYK | 著者 | Han, S, Chang, J. | 登録日 | 2015-06-15 | 公開日 | 2015-10-07 | 最終更新日 | 2016-02-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP). Chemmedchem, 11, 2016
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5LKA
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![BU of 5lka by Molmil](/molmil-images/mine/5lka) | Crystal structure of haloalkane dehalogenase LinB 140A+143L+177W+211L mutant (LinB86) from Sphingobium japonicum UT26 at 1.3 A resolution | 分子名称: | Haloalkane dehalogenase, THIOCYANATE ION | 著者 | Degtjarik, O, Rezacova, P, Iermak, I, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I. | 登録日 | 2016-07-21 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.298 Å) | 主引用文献 | Engineering a de novo transport tunnel. Acs Catalysis, 2016
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1E6U
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![BU of 1e6u by Molmil](/molmil-images/mine/1e6u) | GDP 4-keto-6-deoxy-D-mannose epimerase reductase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | 著者 | Rosano, C, Izzo, G, Bolognesi, M. | 登録日 | 2000-08-23 | 公開日 | 2000-10-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
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6XAT
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![BU of 6xat by Molmil](/molmil-images/mine/6xat) | Crystal structure of the human FoxP4 DNA binding Domain | 分子名称: | FOXP4 protein, SODIUM ION | 著者 | VIllalobos, P, Castro-Fernandez, V, Medina, E, Gonzalez-Ordenes, F, Maturana, P, Herrera-Morande, A, Ramirez-Sarmiento, C.A, Babul, J. | 登録日 | 2020-06-04 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Unraveling the folding and dimerization properties of the human FoxP subfamily of transcription factors. Febs Lett., 597, 2023
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6XIO
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![BU of 6xio by Molmil](/molmil-images/mine/6xio) | ADP-dependent kinase complex with fructose-6-phosphate and ADPbetaS | 分子名称: | 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, 6-O-phosphono-beta-D-fructofuranose, ADP-dependent phosphofructokinase, ... | 著者 | Munoz, S, Gonzalez-Ordenes, F, Fuentes, N, Maturana, P, Herrera-Morande, A, Villalobos, P, Castro-Fernandez, V. | 登録日 | 2020-06-20 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes. J.Biol.Chem., 296, 2020
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1EBT
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1E7S
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![BU of 1e7s by Molmil](/molmil-images/mine/1e7s) | GDP 4-keto-6-deoxy-D-mannose epimerase reductase K140R | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | 著者 | Rosano, C, Zuccotti, S, Izzo, G, Bolognesi, M. | 登録日 | 2000-09-07 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
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