6XIO

ADP-dependent kinase complex with fructose-6-phosphate and ADPbetaS

Summary for 6XIO

Entry DOI	10.2210/pdb6xio/pdb
Descriptor	ADP-dependent phosphofructokinase, 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, 6-O-phosphono-beta-D-fructofuranose, ... (5 entities in total)
Functional Keywords	ancestral protein reconstruction, adp-dependent sugar kinases family, glucokinase, phosphofructokinase, enzyme evolution, transferase
Biological source	Methanosarcinales archaeon
Total number of polymer chains	1
Total formula weight	58496.43
Authors	Munoz, S.,Gonzalez-Ordenes, F.,Fuentes, N.,Maturana, P.,Herrera-Morande, A.,Villalobos, P.,Castro-Fernandez, V. (deposition date: 2020-06-20, release date: 2021-01-20, Last modification date: 2023-10-18)
Primary citation	Munoz, S.M.,Castro-Fernandez, V.,Guixe, V. Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes. J.Biol.Chem., 296:100219-100219, 2020 Cited by PubMed: 33839685 DOI: 10.1074/jbc.RA120.015376 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.12 Å)

Structure validation