5CFH
human beta-2 microglobulin double mutant W60G-Y63W
Summary for 5CFH
Entry DOI | 10.2210/pdb5cfh/pdb |
Descriptor | Beta-2-microglobulin (2 entities in total) |
Functional Keywords | aggregation propensity, amyloid, beta-sandwitch, fold stability, immune system |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P61769 |
Total number of polymer chains | 1 |
Total formula weight | 11773.23 |
Authors | Sala, B.M.,De Rosa, M.,Bolognesi, M.,Ricagno, S. (deposition date: 2015-07-08, release date: 2016-05-18, Last modification date: 2024-01-10) |
Primary citation | Camilloni, C.,Sala, B.M.,Sormanni, P.,Porcari, R.,Corazza, A.,De Rosa, M.,Zanini, S.,Barbiroli, A.,Esposito, G.,Bolognesi, M.,Bellotti, V.,Vendruscolo, M.,Ricagno, S. Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6:25559-25559, 2016 Cited by PubMed: 27150430DOI: 10.1038/srep25559 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
Download full validation report