5CKG

Human beta-2 microglobulin mutant V85E

Summary for 5CKG

• Entry DOI: 10.2210/pdb5ckg/pdb
• Descriptor: Beta-2-microglobulin, ACETATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: aggregation propensity, amyloid, beta-sandwitch, fold stability, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : P61769
• Total number of polymer chains: 2
• Total formula weight: 24028.86

Authors

Sala, B.M.,De Rosa, M.,Bolognesi, M.,Ricagno, S. (deposition date: 2015-07-15, release date: 2016-05-18, Last modification date: 2024-01-10)

• Primary citation: Camilloni, C.,Sala, B.M.,Sormanni, P.,Porcari, R.,Corazza, A.,De Rosa, M.,Zanini, S.,Barbiroli, A.,Esposito, G.,Bolognesi, M.,Bellotti, V.,Vendruscolo, M.,Ricagno, S.; Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.; Sci Rep, 6:25559-25559, 2016; PubMed: 27150430; DOI: 10.1038/srep25559

Experimental method

X-RAY DIFFRACTION (1.75 Å)