5CKA
Human beta-2 microglobulin double mutant W60G-N83V
Summary for 5CKA
Entry DOI | 10.2210/pdb5cka/pdb |
Related | 2Z9T 5CFH |
Descriptor | Beta-2-microglobulin, GLYCEROL, ACETATE ION, ... (5 entities in total) |
Functional Keywords | aggregation propensity, amyloid, beta-sandwitch, fold stability, immune system |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P61769 |
Total number of polymer chains | 1 |
Total formula weight | 12143.62 |
Authors | Sala, B.M.,De Rosa, M.,Bolognesi, M.,Ricagno, S. (deposition date: 2015-07-15, release date: 2016-05-18, Last modification date: 2024-01-10) |
Primary citation | Camilloni, C.,Sala, B.M.,Sormanni, P.,Porcari, R.,Corazza, A.,De Rosa, M.,Zanini, S.,Barbiroli, A.,Esposito, G.,Bolognesi, M.,Bellotti, V.,Vendruscolo, M.,Ricagno, S. Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6:25559-25559, 2016 Cited by PubMed: 27150430DOI: 10.1038/srep25559 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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