4L99
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![BU of 4l99 by Molmil](/molmil-images/mine/4l99) | Structure of the RBP from lactococcal phage 1358 in complex with glycerol | 分子名称: | GLYCEROL, Receptor Binding Protein, ZINC ION | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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4L92
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![BU of 4l92 by Molmil](/molmil-images/mine/4l92) | Structure of the RBP from lactococcal phage 1358 in complex with 2 GlcNAc molecules | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor Binding Protein, ... | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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4L9B
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![BU of 4l9b by Molmil](/molmil-images/mine/4l9b) | Structure of native RBP from lactococcal phage 1358 (CsI derivative) | 分子名称: | CESIUM ION, Receptor Binding Protein | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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4KYB
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![BU of 4kyb by Molmil](/molmil-images/mine/4kyb) | Crystal Structure of de novo designed serine hydrolase OSH55.14_E3, Northeast Structural Genomics Consortium Target OR342 | 分子名称: | Designed Protein OR342, PHOSPHATE ION | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Lee, D, Raja, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-28 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.909 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR342 To be Published
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4L97
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![BU of 4l97 by Molmil](/molmil-images/mine/4l97) | Structure of the RBP of lactococcal phage 1358 in complex with glucose-1-phosphate | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, Receptor Binding Protein | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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3HG0
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![BU of 3hg0 by Molmil](/molmil-images/mine/3hg0) | Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1 | 分子名称: | Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20 | 著者 | Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C. | 登録日 | 2009-05-13 | 公開日 | 2009-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J.Biol.Chem., 284, 2009
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4J4Z
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![BU of 4j4z by Molmil](/molmil-images/mine/4j4z) | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Designed serine hydrolase variant OSH55.4_H1.2, ... | 著者 | Kuzin, A.P, Lew, S, Rajagopalan, S, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-07 | 公開日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 To be Published
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6XUH
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![BU of 6xuh by Molmil](/molmil-images/mine/6xuh) | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | 分子名称: | (2R,3R,4S)-5-((2-aminoethyl)amino)-2,3,4-trihydroxy-5-oxopentyl dihydrogen phosphate, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase | 著者 | Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. | 登録日 | 2020-01-20 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies. Bioorg.Chem., 102, 2020
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4L0J
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![BU of 4l0j by Molmil](/molmil-images/mine/4l0j) | Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems | 分子名称: | DNA helicase I, MAGNESIUM ION, SULFATE ION | 著者 | Redzej, A, Ilangovan, A, Lang, S, Gruber, C.J, Topf, M, Zangger, K, Zechner, E.L, Waksman, G. | 登録日 | 2013-05-31 | 公開日 | 2013-06-19 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems. Mol.Microbiol., 89, 2013
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7R7P
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![BU of 7r7p by Molmil](/molmil-images/mine/7r7p) | Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6) | 分子名称: | 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | 著者 | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | 登録日 | 2021-06-25 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14, 2023
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7R7Q
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![BU of 7r7q by Molmil](/molmil-images/mine/7r7q) | Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6) | 分子名称: | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | 著者 | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | 登録日 | 2021-06-25 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14, 2023
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6XUI
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![BU of 6xui by Molmil](/molmil-images/mine/6xui) | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5-PHOSPHOARABINONIC ACID, GLYCEROL, ... | 著者 | Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. | 登録日 | 2020-01-20 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies. Bioorg.Chem., 102, 2020
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4JBC
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![BU of 4jbc by Molmil](/molmil-images/mine/4jbc) | Crystal Structure of the computationally designed serine hydrolase 3mmj_2, Northeast Structural Genomics Consortium (NESG) Target OR318 | 分子名称: | PHOSPHATE ION, designed serine hydrolase 3mmj_2 | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Baker, D, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-19 | 公開日 | 2013-03-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | Crystal Structure of the computationally designed serine hydrolase 3mmj_2, Northeast Structural Genomics Consortium (NESG) Target OR318 To be Published
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4JGK
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![BU of 4jgk by Molmil](/molmil-images/mine/4jgk) | Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 | 分子名称: | evolved variant of a designed serine hydrolase | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-03-01 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.883 Å) | 主引用文献 | Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 To be Published
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4K0C
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![BU of 4k0c by Molmil](/molmil-images/mine/4k0c) | Crystal Structure of the computationally designed serine hydrolase. Northeast Structural Genomics Consortium (NESG) Target OR317 | 分子名称: | designed serine hydrolase | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-03 | 公開日 | 2013-04-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR317 To be Published
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4W66
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![BU of 4w66 by Molmil](/molmil-images/mine/4w66) | |
4UQY
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![BU of 4uqy by Molmil](/molmil-images/mine/4uqy) | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | 分子名称: | HSIB1, HSIE1 | 著者 | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | 登録日 | 2014-06-25 | 公開日 | 2014-10-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes. J.Biol.Chem., 289, 2014
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2OTD
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![BU of 2otd by Molmil](/molmil-images/mine/2otd) | The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a | 分子名称: | Glycerophosphodiester phosphodiesterase, PHOSPHATE ION | 著者 | Zhang, R, Wu, R, Clancy, S, Jiang, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-02-07 | 公開日 | 2007-03-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a To be Published
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4WER
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![BU of 4wer by Molmil](/molmil-images/mine/4wer) | Crystal structure of diacylglycerol kinase catalytic domain protein from Enterococcus faecalis V583 | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Diacylglycerol kinase catalytic domain protein | 著者 | Chang, C, Clancy, S, Hatzos-Skintges, C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-09-10 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of diacylglycerol kinase catalytic domain protein from Enterococcus faecalis V583 To Be Published
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1ZRU
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![BU of 1zru by Molmil](/molmil-images/mine/1zru) | structure of the lactophage p2 receptor binding protein in complex with glycerol | 分子名称: | GLYCEROL, lactophage p2 receptor binding protein | 著者 | Spinelli, S, Tremblay, D.M, Tegoni, M, Blangy, S, Huyghe, C, Desmyter, A, Labrie, S, de Haard, H, Moineau, S, Cambillau, C, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-05-22 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Receptor-binding protein of Lactococcus lactis phages: identification and characterization of the saccharide receptor-binding site. J.Bacteriol., 188, 2006
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2R2A
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![BU of 2r2a by Molmil](/molmil-images/mine/2r2a) | Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis | 分子名称: | SULFATE ION, Uncharacterized protein | 著者 | Osipiuk, J, Patterson, S, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-08-24 | 公開日 | 2007-09-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis. To be Published
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4Y0D
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![BU of 4y0d by Molmil](/molmil-images/mine/4y0d) | Gamma-aminobutyric acid aminotransferase inactivated by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) | 分子名称: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | 著者 | Rui, W, Ruslan, S, Hyunbeom, L, Emma, H.D, Jose, I.J, Neil, K, Richard, B.S, Dali, L. | 登録日 | 2015-02-05 | 公開日 | 2015-02-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) J. Am. Chem. Soc., 2015
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4XLT
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![BU of 4xlt by Molmil](/molmil-images/mine/4xlt) | Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 | 分子名称: | Response regulator receiver protein | 著者 | Chang, C, Cuff, M, Holowicki, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-01-13 | 公開日 | 2015-01-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 To Be Published
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4Y0H
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![BU of 4y0h by Molmil](/molmil-images/mine/4y0h) | Gamma-aminobutyric acid aminotransferase inactivated by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) | 分子名称: | 4-aminobutyrate aminotransferase, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Rui, W, Ruslan, S, Hyunbeom, L, Emma, H.D, Jose, I.J, Neil, K, Richard, B.S, Dali, L. | 登録日 | 2015-02-06 | 公開日 | 2015-03-11 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) J. Am. Chem. Soc., 2015
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5EH0
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![BU of 5eh0 by Molmil](/molmil-images/mine/5eh0) | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | 分子名称: | DIMETHYL SULFOXIDE, Dual specificity protein kinase TTK, N2-(2-Methoxy-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine | 著者 | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | 登録日 | 2015-10-27 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J.Med.Chem., 59, 2016
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