7R7Q
Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6)
Summary for 7R7Q
Entry DOI | 10.2210/pdb7r7q/pdb |
NMR Information | BMRB: 30930 |
Descriptor | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE (2 entities in total) |
Functional Keywords | hiv-1 capsid, maturation inhibitors, hiv-aids, protein binding |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 6 |
Total formula weight | 67228.07 |
Authors | Sarkar, S.,Zadrozny, K.K.,Zadorozhnyi, R.,Russell, R.W.,Quinn, C.M.,Kleinpeter, A.,Ablan, S.,Meshkin, H.,Perilla, J.R.,Ganser-Pornillos, B.K.,Pornillos, O.,Freed, E.O.,Gronenborn, A.M.,Polenova, T. (deposition date: 2021-06-25, release date: 2023-02-15, Last modification date: 2023-03-22) |
Primary citation | Sarkar, S.,Zadrozny, K.K.,Zadorozhnyi, R.,Russell, R.W.,Quinn, C.M.,Kleinpeter, A.,Ablan, S.,Meshkin, H.,Perilla, J.R.,Freed, E.O.,Ganser-Pornillos, B.K.,Pornillos, O.,Gronenborn, A.M.,Polenova, T. Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14:1237-1237, 2023 Cited by PubMed: 36871077DOI: 10.1038/s41467-023-36569-y PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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