4Y0H

Gamma-aminobutyric acid aminotransferase inactivated by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115)

Summary for 4Y0H

• Entry DOI: 10.2210/pdb4y0h/pdb
• Related: 4Y0D
• Descriptor: 4-aminobutyrate aminotransferase, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: gaba-at, inactivator, transferase
• Biological source: Sus scrofa (Pig)
• Cellular location: Mitochondrion matrix: P80147
• Total number of polymer chains: 4
• Total formula weight: 211232.18

Authors

Rui, W.,Ruslan, S.,Hyunbeom, L.,Emma, H.D.,Jose, I.J.,Neil, K.,Richard, B.S.,Dali, L. (deposition date: 2015-02-06, release date: 2015-03-11, Last modification date: 2017-11-22)

• Primary citation: Hyunbeom, L.,Emma, H.D.,Rui, W.,Ruslan, S.,Jose, I.J.,Dali, L.,Neil, K.,Richard, B.S.; Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115); J. Am. Chem. Soc., 2015; PubMed: 25616005; DOI: 10.1021/ja512299n

Experimental method

X-RAY DIFFRACTION (1.63 Å)