4Y0H
Gamma-aminobutyric acid aminotransferase inactivated by (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 4-aminobutyrate aminotransferase, mitochondrial | polymer | 463 | 52426.9 | 4 | UniProt (P80147) Pfam (PF00202) | Sus scrofa (Pig) | (S)-3-amino-2-methylpropionate transaminase,GABA aminotransferase,GABA-AT,Gamma-amino-N-butyrate transaminase,GABA-T,L-AIBAT |
| 2 | E, I (A, C) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 3 | F, H, K, L (A, B, C, D) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) | |||
| 4 | G, J (B, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 841 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 472 (UniProt: P80147)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
| Glu 158 | Gln 186 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 209707.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1524.4 | |
| All* | Total formula weight | 211232.2 |
