Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7QWM
DownloadVisualize
BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
DownloadVisualize
BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
DownloadVisualize
BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWL
DownloadVisualize
BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
DownloadVisualize
BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
5ZAJ
DownloadVisualize
BU of 5zaj by Molmil
uPA-31F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZAG
DownloadVisualize
BU of 5zag by Molmil
uPA-BB2-94F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-pyrimidin-5-yl-pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZA8
DownloadVisualize
BU of 5za8 by Molmil
uPA-BB2-27F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(1-methylpyrazol-4-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-06
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZAF
DownloadVisualize
BU of 5zaf by Molmil
uPA-BB2-28F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(furan-3-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZA7
DownloadVisualize
BU of 5za7 by Molmil
uPA-HMA
分子名称: 3-azanyl-5-(azepan-1-yl)-N-[bis(azanyl)methylidene]-6-chloranyl-pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-06
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZAE
DownloadVisualize
BU of 5zae by Molmil
uPA-6F-HMA
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(furan-2-yl)pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZC5
DownloadVisualize
BU of 5zc5 by Molmil
uPA-NU-09F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(4-fluoranyl-1-benzofuran-2-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Jiang, L.G, Buckley, B.J, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-15
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZAH
DownloadVisualize
BU of 5zah by Molmil
uPA-BB2-30F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
5ZA9
DownloadVisualize
BU of 5za9 by Molmil
uPA-BB2-50F
分子名称: 3-azanyl-5-(azepan-1-yl)-6-(1-benzofuran-2-yl)-Ncarbamimidoyl-pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-07
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
6VYO
DownloadVisualize
BU of 6vyo by Molmil
Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-02-27
公開日2020-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
6WKP
DownloadVisualize
BU of 6wkp by Molmil
Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION
著者Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-16
公開日2020-04-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7U6R
DownloadVisualize
BU of 7u6r by Molmil
Cryo-EM structure of PDF-2180 Spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PDF-2180 Spike glycoprotein
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-03-05
公開日2022-11-30
最終更新日2023-01-04
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Nature, 612, 2022
7V0E
DownloadVisualize
BU of 7v0e by Molmil
Crystal structure of the macro-oligomeric form of DNMT3B methyltransferase domain.
分子名称: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE
著者Gao, L, Lu, J, Song, J.
登録日2022-05-10
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.27016377 Å)
主引用文献Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations.
Nat Commun, 13, 2022
1G6R
DownloadVisualize
BU of 1g6r by Molmil
A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX
分子名称: ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ...
著者Degano, M, Garcia, K.C, Apostolopoulos, V, Rudolph, M.G, Teyton, L, Wilson, I.A.
登録日2000-11-07
公開日2000-11-15
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.
Immunity, 12, 2000
3U74
DownloadVisualize
BU of 3u74 by Molmil
Crystal structure of stabilized human uPAR mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor
著者Huang, M.D, Xu, X, Yuan, C.
登録日2011-10-13
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
4H42
DownloadVisualize
BU of 4h42 by Molmil
Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, N-[(2-amino-1,3-benzothiazol-6-yl)carbonyl]glycine, Urokinase-type plasminogen activator
著者Yu, H.-Y, Gao, D, Zhang, X, Jiang, L.-G, Hong, Z.-B, Yuan, C, Fang, X, Wang, J.-D, Huang, M.-D.
登録日2012-09-14
公開日2013-10-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA
CHIN.J.STRUCT.CHEM., 32, 2013
5BRR
DownloadVisualize
BU of 5brr by Molmil
Michaelis complex of tPA-S195A:PAI-1
分子名称: GLYCEROL, Plasminogen activator inhibitor 1, TRIETHYLENE GLYCOL, ...
著者Gong, L.
登録日2015-06-01
公開日2015-09-02
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1
J.Biol.Chem., 290, 2015
8D0Z
DownloadVisualize
BU of 8d0z by Molmil
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S728-1157 Fab heavy chain variable region, S728-1157 Fab light chain variable region, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2022-05-26
公開日2023-03-22
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants.
J.Clin.Invest., 133, 2023
2CKB
DownloadVisualize
BU of 2ckb by Molmil
STRUCTURE OF THE 2C/KB/DEV8 COMPLEX
分子名称: ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ...
著者Garcia, K.C, Degano, M, Wilson, I.A.
登録日1998-01-14
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
6UCA
DownloadVisualize
BU of 6uca by Molmil
Crystal structure of human ZCCHC4 in complex with SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, rRNA N6-adenosine-methyltransferase ZCCHC4
著者Lu, J.W, Ren, W.D, Huang, M.J, Gao, L, Li, D.X, Wang, G.G, Song, J.
登録日2019-09-15
公開日2019-10-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA.
Nat Commun, 10, 2019

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon