5IC8
 
 | | Structure of UTP6 | | 分子名称: | Putative uncharacterized protein | | 著者 | Zhang, C, Ye, K. | | 登録日 | 2016-02-23 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
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5APK
 | | Ligand complex of RORg LBD | | 分子名称: | 2-CHLORO-6-FLUORO-N-[4-[3-(TRIFLUOROMETHYL)PHENYL]SULFONYL-3,5-DIHYDRO-2H-1,4-BENZOXAZEPIN-7-YL]BENZAMIDE, NUCLEAR RECEPTOR ROR-GAMMA | | 著者 | Xue, Y, Aagaard, A, Narjes, F. | | 登録日 | 2015-09-16 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma.
ChemMedChem, 11, 2016
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5APJ
 | | Ligand complex of RORg LBD | | 分子名称: | 2-CHLORO-6-FLUORO-N-[4-[3-(TRIFLUOROMETHYL)PHENYL]SULFONYL-3,5-DIHYDRO-2H-1,4-BENZOXAZEPIN-7-YL]BENZAMIDE, NUCLEAR RECEPTOR COACTIVATOR 2, NUCLEAR RECEPTOR ROR-GAMMA, ... | | 著者 | Xue, Y, Aagaard, A, Narjes, F. | | 登録日 | 2015-09-16 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma.
ChemMedChem, 11, 2016
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5APH
 | | Ligand complex of RORg LBD | | 分子名称: | DIMETHYL SULFOXIDE, N-(2-FLUOROPHENYL)-4-[(4-FLUOROPHENYL)SULFONYL]-2,3,4,5-TETRAHYDRO-1,4-BENZOXAZEPIN-6-AMINE, NUCLEAR RECEPTOR COACTIVATOR 2, ... | | 著者 | Xue, Y, Aagaard, A, Narjes, F. | | 登録日 | 2015-09-16 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma.
ChemMedChem, 11, 2016
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7VPP
 | | Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ji, W, Xu, Y, Zhang, S. | | 登録日 | 2021-10-17 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nat Commun, 13, 2022
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7VPQ
 | | Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ji, W, Xu, Y, Zhang, S. | | 登録日 | 2021-10-17 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nat Commun, 13, 2022
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7VOC
 | | The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S | | 分子名称: | (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ... | | 著者 | Hou, X.L, Zhou, J.H. | | 登録日 | 2021-10-13 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.62005424 Å) | | 主引用文献 | Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
J.Am.Chem.Soc., 144, 2022
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7VOB
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5H5Z
 | | Crystal structure of bony fish MHC class I, peptide and B2m II | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide chain | | 著者 | Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C. | | 登録日 | 2016-11-10 | | 公開日 | 2017-11-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish.
Iscience, 23, 2020
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5HJJ
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5HJK
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5HJM
 | | Crystal Structure of Pyrococcus abyssi Trm5a complexed with MTA | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, ACETATE ION, HOMOSERINE LACTONE, ... | | 著者 | Xie, W, Wang, C, Jia, Q. | | 登録日 | 2016-01-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Crystal structures of the bifunctional tRNA methyltransferase Trm5a
Sci Rep, 6, 2016
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5HJI
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5ZXF
 | | The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a | | 分子名称: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Cheng, X.Y, Su, Z.D, Pi, N, Cao, C.Z, Zhao, Z.T, Zhou, J.J, Chen, R, Kuang, Z.K, Huang, Y.Q. | | 登録日 | 2018-05-19 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a
To Be Published
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5WWM
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5Z02
 | | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a | | 分子名称: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Su, Z.D, Cheng, X.Y, Chen, R, Pi, N. | | 登録日 | 2017-12-18 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a
to be published
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5WXL
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7WIJ
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5WWN
 | | Crystal structure of Tsr1 | | 分子名称: | Ribosome biogenesis protein TSR1, SULFATE ION | | 著者 | Ye, K, Wang, B. | | 登録日 | 2017-01-03 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WXM
 | | Crystal structure of the Imp3 and Mpp10 complex | | 分子名称: | SULFATE ION, U3 small nucleolar RNA-associated protein MPP10, U3 small nucleolar ribonucleoprotein protein IMP3 | | 著者 | Ye, K, Zheng, S. | | 登録日 | 2017-01-07 | | 公開日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WWO
 | | Crystal structure of Enp1 | | 分子名称: | Essential nuclear protein 1, Protein LTV1 | | 著者 | Ye, K, Zhang, W. | | 登録日 | 2017-01-03 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WYJ
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | 著者 | Ye, K, Zhu, X, Sun, Q. | | 登録日 | 2017-01-13 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-10-09 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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5WYK
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | 著者 | Ye, K, Zhu, X, Sun, Q. | | 登録日 | 2017-01-13 | | 公開日 | 2017-03-29 | | 最終更新日 | 2017-05-17 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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4GHI
 | | Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with a benzoxadiazole antagonist | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | | 著者 | Scheuermann, T.H, Key, J, Tambar, U.K, Bruick, R.K, Gardner, K.H. | | 登録日 | 2012-08-07 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Allosteric inhibition of hypoxia inducible factor-2 with small molecules.
Nat.Chem.Biol., 9, 2013
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4NSQ
 | | Crystal structure of PCAF | | 分子名称: | COENZYME A, Histone acetyltransferase KAT2B | | 著者 | Lin, J.Y, Cai, Y.F. | | 登録日 | 2013-11-28 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3108 Å) | | 主引用文献 | Dimeric structure of p300/CBP associated factor.
Bmc Struct.Biol., 14, 2014
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