7VPQ

Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans

Summary for 7VPQ

• Entry DOI: 10.2210/pdb7vpq/pdb
• Descriptor: Aminopeptidase N, Spike protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: porcine deltacoronavirus, receptor, cross-species transmission, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 361878.77

Authors

Ji, W.,Xu, Y.,Zhang, S. (deposition date: 2021-10-17, release date: 2022-03-16, Last modification date: 2023-11-29)

• Primary citation: Ji, W.,Peng, Q.,Fang, X.,Li, Z.,Li, Y.,Xu, C.,Zhao, S.,Li, J.,Chen, R.,Mo, G.,Wei, Z.,Xu, Y.,Li, B.,Zhang, S.; Structures of a deltacoronavirus spike protein bound to porcine and human receptors.; Nat Commun, 13:1467-1467, 2022; PubMed: 35304871; DOI: 10.1038/s41467-022-29062-5

Experimental method

X-RAY DIFFRACTION (3.1 Å)