4NSQ

Crystal structure of PCAF

Summary for 4NSQ

• Entry DOI: 10.2210/pdb4nsq/pdb
• Descriptor: Histone acetyltransferase KAT2B, COENZYME A (2 entities in total)
• Functional Keywords: acetyltransferase, coa binding, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): Q92831
• Total number of polymer chains: 4
• Total formula weight: 90423.80

Authors

Lin, J.Y.,Cai, Y.F. (deposition date: 2013-11-28, release date: 2014-03-05, Last modification date: 2024-02-28)

Primary citation

Shi, S.,Lin, J.,Cai, Y.,Yu, J.,Hong, H.,Ji, K.,Downey, J.S.,Lu, X.,Chen, R.,Han, J.,Han, A.
Dimeric structure of p300/CBP associated factor.
Bmc Struct.Biol., 14:2-2, 2014

PubMed Abstract: p300/CBP associating factor (PCAF, also known as KAT2B for lysine acetyltransferase 2B) is a catalytic subunit of megadalton metazoan complex ATAC (Ada-Two-A containing complex) for acetylation of histones. However, relatively little is known about the regulation of the enzymatic activity of PCAF.

PubMed: 24423233
DOI: 10.1186/1472-6807-14-2

Experimental method

X-RAY DIFFRACTION (2.3108 Å)