4NSQ
Crystal structure of PCAF
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0004402 | molecular_function | histone acetyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0004402 | molecular_function | histone acetyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE COA A 700 |
| Chain | Residue |
| A | GLN525 |
| A | TYR585 |
| A | GLY586 |
| A | THR587 |
| A | TYR612 |
| A | ALA613 |
| A | GLY615 |
| A | TYR616 |
| A | PHE617 |
| A | LYS619 |
| A | LEU526 |
| A | CYS574 |
| A | ALA575 |
| A | VAL576 |
| A | GLN581 |
| A | VAL582 |
| A | LYS583 |
| A | GLY584 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE COA B 700 |
| Chain | Residue |
| B | GLN525 |
| B | LEU526 |
| B | CYS574 |
| B | ALA575 |
| B | VAL576 |
| B | GLN581 |
| B | VAL582 |
| B | LYS583 |
| B | GLY584 |
| B | TYR585 |
| B | GLY586 |
| B | THR587 |
| B | TYR612 |
| B | ALA613 |
| B | GLY615 |
| B | TYR616 |
| B | PHE617 |
| B | LYS619 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE COA C 700 |
| Chain | Residue |
| C | GLN525 |
| C | LEU526 |
| C | CYS574 |
| C | ALA575 |
| C | VAL576 |
| C | GLN581 |
| C | VAL582 |
| C | LYS583 |
| C | GLY584 |
| C | TYR585 |
| C | GLY586 |
| C | THR587 |
| C | TYR612 |
| C | ALA613 |
| C | GLY615 |
| C | TYR616 |
| C | PHE617 |
| C | LYS619 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE COA D 700 |
| Chain | Residue |
| D | GLN525 |
| D | CYS574 |
| D | ALA575 |
| D | VAL576 |
| D | GLN581 |
| D | VAL582 |
| D | LYS583 |
| D | GLY584 |
| D | TYR585 |
| D | GLY586 |
| D | THR587 |
| D | ALA613 |
| D | TYR616 |
| D | PHE617 |
| D | LYS619 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000303|PubMed:10393169 |
| Chain | Residue | Details |
| A | GLU570 | |
| B | GLU570 | |
| C | GLU570 | |
| D | GLU570 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10393169 |
| Chain | Residue | Details |
| A | CYS574 | |
| D | CYS574 | |
| D | GLN581 | |
| D | TYR612 | |
| A | GLN581 | |
| A | TYR612 | |
| B | CYS574 | |
| B | GLN581 | |
| B | TYR612 | |
| C | CYS574 | |
| C | GLN581 | |
| C | TYR612 |
