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7USE
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BU of 7use by Molmil
Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site
分子名称: Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ding, B, Yang, S, Chen, B, Chowdhury, S.
登録日2022-04-25
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
7USC
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BU of 7usc by Molmil
Cryo-EM structure of WAVE Regulatory Complex
分子名称: Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, ...
著者Ding, B, Yang, S, Chen, B, Chowdhury, S.
登録日2022-04-25
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
7USD
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BU of 7usd by Molmil
Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex
分子名称: Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ding, B, Yang, S, Chen, B, Chowdhury, S.
登録日2022-04-25
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
7D88
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BU of 7d88 by Molmil
Crystal structure of a novel thermostable GH10 xylanase XynA
分子名称: Beta-xylanase, CALCIUM ION
著者Xie, W, Yu, Q, Wang, C.
登録日2020-10-07
公開日2021-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.34482026 Å)
主引用文献Insights into the Catalytic Mechanism of a Novel XynA and Structure-Based Engineering for Improving Bifunctional Activities.
Biochemistry, 60, 2021
7D89
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BU of 7d89 by Molmil
Crystal structure of an inactivated double mutant (E182AE280A) of a novel thermostable GH10 xylanase XynA
分子名称: Beta-xylanase, CALCIUM ION
著者Xie, W, Yu, Q, Wang, C.
登録日2020-10-07
公開日2021-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89384079 Å)
主引用文献Insights into the Catalytic Mechanism of a Novel XynA and Structure-Based Engineering for Improving Bifunctional Activities.
Biochemistry, 60, 2021
1QFW
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BU of 1qfw by Molmil
TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ...
著者Tegoni, M, Spinelli, S, Cambillau, C.
登録日1999-04-15
公開日2000-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
7VQM
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BU of 7vqm by Molmil
GH2 beta-galacturonate AqGalA in complex with galacturonide
分子名称: CHLORIDE ION, GH2 beta-galacturonate AqGalA, beta-D-galactopyranuronic acid
著者Yang, J.
登録日2021-10-20
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Biochemical Basis of a Marine Bacterial Glycoside Hydrolase Family 2 beta-Glycosidase with Broad Substrate Specificity
Appl.Environ.Microbiol., 88, 2022
7U9X
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BU of 7u9x by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9Q
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BU of 7u9q by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9T
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BU of 7u9t by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA9
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BU of 7ua9 by Molmil
Structure of dephosphorylated human RyR2 in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA3
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BU of 7ua3 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA1
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BU of 7ua1 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA4
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BU of 7ua4 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA5
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BU of 7ua5 by Molmil
Structure of dephosphorylated human RyR2 in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9R
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BU of 7u9r by Molmil
Structure of PKA phosphorylated human RyR2 in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9Z
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BU of 7u9z by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7VCK
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BU of 7vck by Molmil
NMR solution structures of a hairpin formed by GGCCTG repeats
分子名称: DNA (5'-D(*GP*GP*CP*CP*TP*GP*GP*GP*CP*CP*TP*G)-3'), SODIUM ION
著者Yi, J, Wan, L, Guo, P.
登録日2021-09-03
公開日2022-02-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structures of d(GGCCTG)n repeats associated with spinocerebellar ataxia type 36.
Int.J.Biol.Macromol., 201, 2022
7VJS
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BU of 7vjs by Molmil
Human AlkB homolog ALKBH6 in complex with Tris and Ni
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, NICKEL (II) ION
著者Ma, L, Chen, Z.
登録日2021-09-28
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6.
J.Biol.Chem., 298, 2022
7VJV
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BU of 7vjv by Molmil
Human AlkB homolog ALKBH6 in complex with alpha-katoglutarate and Mn
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, MANGANESE (II) ION
著者Ma, L, Chen, Z.
登録日2021-09-29
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6.
J.Biol.Chem., 298, 2022
6L3F
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BU of 6l3f by Molmil
The structure of UTP:RNA uridylyltransferase 1 (URT1) in in Arabidopsis
分子名称: UTP:RNA uridylyltransferase 1
著者Lingru, Z.
登録日2019-10-10
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Crystal structure of Arabidopsis terminal uridylyl transferase URT1.
Biochem.Biophys.Res.Commun., 524, 2020
6L8K
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BU of 6l8k by Molmil
Structure of URT1 in complex with UTP
分子名称: URIDINE 5'-TRIPHOSPHATE, UTP:RNA uridylyltransferase 1
著者Lingru, Z.
登録日2019-11-06
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Crystal structure of Arabidopsis terminal uridylyl transferase URT1.
Biochem.Biophys.Res.Commun., 524, 2020
6M07
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BU of 6m07 by Molmil
Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor
分子名称: (2S)-2-[(E)-3-[2-(diethylamino)ethyl-[[4-[4-(trifluoromethyl)-2-[2,2,2-tris(fluoranyl)ethoxy]phenyl]phenyl]methyl]amino]-1-oxidanyl-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid, Platelet-activating factor acetylhydrolase
著者Hu, H.C, Xu, Y.C.
登録日2020-02-20
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach.
J.Med.Chem., 63, 2020
6M08
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Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor.
分子名称: (2S)-2-[(Z)-3-[2-(diethylamino)ethyl-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]amino]-1-oxidanyl-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid, Platelet-activating factor acetylhydrolase
著者Hu, H.C, Xu, Y.C.
登録日2020-02-20
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach.
J.Med.Chem., 63, 2020
7V1L
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Structure of sNASP core in complex with H3 alpha3 helix peptide
分子名称: H3 alpha3 helix peptide, Isoform 2 of Nuclear autoantigenic sperm protein
著者Bao, H, Huang, H.
登録日2021-08-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.849 Å)
主引用文献NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022

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