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7U9R

Structure of PKA phosphorylated human RyR2 in the open state

This is a non-PDB format compatible entry.
Summary for 7U9R
Entry DOI10.2210/pdb7u9r/pdb
EMDB information26407
DescriptorPeptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION, ... (6 entities in total)
Functional Keywordscalcium channel, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains8
Total formula weight2313426.34
Authors
Miotto, M.C.,Marks, A.R. (deposition date: 2022-03-11, release date: 2022-08-03)
Primary citationMiotto, M.C.,Weninger, G.,Dridi, H.,Yuan, Q.,Liu, Y.,Wronska, A.,Melville, Z.,Sittenfeld, L.,Reiken, S.,Marks, A.R.
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8:eabo1272-eabo1272, 2022
Cited by
PubMed: 35857850
DOI: 10.1126/sciadv.abo1272
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.69 Å)
Structure validation

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