7U9Z
Structure of PKA phosphorylated human RyR2-R2474S in the open state
This is a non-PDB format compatible entry.
Summary for 7U9Z
Entry DOI | 10.2210/pdb7u9z/pdb |
EMDB information | 26410 |
Descriptor | Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... (6 entities in total) |
Functional Keywords | calcium channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 2313145.84 |
Authors | |
Primary citation | Miotto, M.C.,Weninger, G.,Dridi, H.,Yuan, Q.,Liu, Y.,Wronska, A.,Melville, Z.,Sittenfeld, L.,Reiken, S.,Marks, A.R. Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8:eabo1272-eabo1272, 2022 Cited by PubMed: 35857850DOI: 10.1126/sciadv.abo1272 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.29 Å) |
Structure validation
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