1QFW

TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT

Summary for 1QFW

DescriptorGONADOTROPIN ALPHA SUBUNIT, GONADOTROPHIN BETA SUBUNIT, ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ... (7 entities in total)
Functional Keywordsglycoprotein hormone, stimulation of production of progesterone, fvs specifically directed against alpha and beta subunit, immune system
Biological sourceMus musculus (house mouse)
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Cellular locationSecreted P01215 P01233
Total number of polymer chains6
Total molecular weight77152.53
Authors
Tegoni, M.,Spinelli, S.,Cambillau, C. (deposition date: 1999-04-15, release date: 2000-04-26, Last modification date: 2011-07-13)
Primary citation
Tegoni, M.,Spinelli, S.,Verhoeyen, M.,Davis, P.,Cambillau, C.
Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289:1375-1385, 1999
PubMed: 10373373 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1999.2845
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers384.7%17.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1qfw
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